[1]刘 超,朱丽萍,张克宁,等.1.0T开放式磁共振引导经皮同轴胰腺病变穿刺活检的初步应用[J].介入放射学杂志,2019,28(11):1081-1086.
 LIU Chao,ZHU Liping,ZHANG Kening,et al.Preliminary application of 1.0T open MR- guided percutaneous coaxial needle biopsy of pancreatic lesions[J].journal interventional radiology,2019,28(11):1081-1086.
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1.0T开放式磁共振引导经皮同轴胰腺病变穿刺活检的初步应用()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
28
期数:
2019年11期
页码:
1081-1086
栏目:
临床研究
出版日期:
2019-11-25

文章信息/Info

Title:
Preliminary application of 1.0T open MR- guided percutaneous coaxial needle biopsy of pancreatic lesions
作者:
刘 超 朱丽萍 张克宁 何祥萌 柳 明 许玉军 董 青 邱红梅 李成利
Author(s):
LIU Chao ZHU Liping ZHANG Kening HE Xiangmeng LIU Ming XU Yujun DONG Qing QIU Hongmei LI Chengli.
Department of Minimally Invasive Therapy of Tumor, Tai’an Municipal Central Hospital, Tai’an, Shandong Province 271000, China
关键词:
【关键词】 磁共振引导 介入放射学 胰腺占位
文献标志码:
A
摘要:
【摘要】 目的 优化选择1.0 T 开放式MR引导经皮同轴胰腺病变穿刺活检的多模态序列及评估其可行性、准确性和安全性。方法 2016年1月至2018年3月, 42例胰腺病变患者,采用开放式1.0 T高场强磁共振扫描仪引导下经皮同轴切割针穿刺活检操作。术前增强CT或MR评估,19例胰头病变(19/42, 45.2%),10例胰体病变(10/42, 23.8%), 13例胰尾病变(13/42, 31.0%),病变最长径平均(2.9±0.8) cm(2.0~5.3 cm)。局麻下,MR扫描联合鱼油胶囊矩阵定位网格确定活检针穿刺入路点并引导穿刺。T2WI- TSE(Turbo Spin Echo T2加权序列)用于病灶定位;PD- TSE(Turbo Spin Echo prodensity加权序列)进行穿刺过程中显示穿刺针方向和实际针尖的位置;增强扫描T1WI- TFE(Turbo Field Echo T1加权序列)在需要区分病灶及坏死灶时,作为互补序列确定穿刺靶区;活检后10 min内,采用脂肪抑制T2WI- TSE序列扫描确认是否存在术后并发症发生。通过手术和临床随访至少12个月确认最终诊断。计算准确率、灵敏度和特异度,记录并发症。 结果 1.0 T MR 多模态序列扫描引导与监控下,对全组42例患者均成功实施穿刺活检,获取的样本足以用于组织病理学诊断。穿刺活检病理显示34例(80.9%)患者为恶性胰腺肿瘤,8例(19.1%)为良性胰腺病变。经手术和临床随访证实,37例诊断为胰腺恶性肿瘤,5例为良性疾病,3例活检结果为假阴性。活检诊断准确率92.9%(39/42),灵敏度91.9%(34/37),特异度100%,阳性预测值100%,阴性预测值62.5%。全部患者穿刺活检耐受良好,3例患者在手术后出现轻微的胰周出血,未出现严重并发症。 结论 1.0 T开放式高场强MR多模态序列引导与监控对胰腺病变经皮穿刺活检具有很高的诊断准确率,在临床实践中是可行和安全的。

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备注/Memo

备注/Memo:
(收稿日期:2019- 06- 04)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2019-11-18