[1]林昭旺,林征宇,陈 锦,等.兔肝VX2肿瘤射频消融后即时MRI与病理相关性[J].介入放射学杂志,2019,28(11):1076-1080.
 LIN Zhaowang,LIN Zhengyu,CHEN Jin,et al.The correlation between MRI manifestations immediate after RFA and pathological findings of rabbit liver VX2 tumors[J].journal interventional radiology,2019,28(11):1076-1080.
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
28
期数:
2019年11期
页码:
1076-1080
栏目:
实验研究
出版日期:
2019-11-25

文章信息/Info

Title:
The correlation between MRI manifestations immediate after RFA and pathological findings of rabbit liver VX2 tumors
作者:
林昭旺 林征宇 陈 锦 吴志斌 陈 杰 汪 强
Author(s):
LIN Zhaowang LIN Zhengyu CHEN Jin WU Zhibin CHEN Jie WANG Qiang.
Imaging Department, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, Fujian Province 350025, China
关键词:
【关键词】 动物实验 肝肿瘤 射频消融 磁共振成像 病理学
文献标志码:
A
摘要:
【摘要】 目的 通过对比活体组和处死组兔肝VX2肿瘤RFA后MRI和病理学表现,探讨肝肿瘤RFA后即时MRI与病理学表现的相关性。 方法 观察活体组和处死组RFA后荷瘤兔肝VX2肿瘤即时MRI和病理学表现。分别检测RFA前MRI T1WI瘤灶最大径、消融灶T1WI中央低信号区最大径、活体组消融灶T1WI周边高信号区最大径、T2WI低信号区最大径、病理标本瘤灶最大径以及肝实质凝固性坏死区最大径,并进行统计学分析。 结果 活体组消融灶T1WI呈靶征,中心呈低信号,周边呈环形包绕高信号,T2WI大体呈低信号;处死组消融灶T1WI靶征较活体组不明显,T2WI大体呈等-稍低信号。苏木精-伊红(HE)染色显示,活体组消融灶肝实质凝固性坏死区肝窦受热扩张充血,肝窦内见充满热损伤红细胞,部分红细胞血红素流失成为空泡状;处死组消融灶肝实质凝固性坏死区肝窦轻度扩张,红细胞数明显少于活体组。统计学分析提示,术前MRI T1WI瘤灶、消融灶T1WI中央低信号区与病理标本瘤灶最大径相对应(P>0.05);活体组消融灶T1WI周边高信号区、T2WI低信号区与病理标本肝实质凝固性坏死区最大径相对应(P>0.05)。 结论 肝肿瘤RFA后即时MR平扫,尤其是T1WI具有明显特征性表现,与术后病理学检查呈良好一致性。

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备注/Memo

备注/Memo:
(收稿日期:2019- 03- 15)
(本文编辑:边 佶)
更新日期/Last Update: 2019-11-18