[1]周晴,何瀚夫,汪晟,等.氩氦刀冷冻消融治疗晚期肺癌的安全性和有效性评价 [J].介入放射学杂志,2020,29(01):70-75.
 ZHOU Qing,HE Hanfu,WANG Sheng,et al.Cryoablation with argon-helium knife for the treatment of advanced lung cancer: evaluation of its safety and effectiveness[J].journal interventional radiology,2020,29(01):70-75.
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氩氦刀冷冻消融治疗晚期肺癌的安全性和有效性评价
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
29
期数:
2020年01
页码:
70-75
栏目:
临床研究
出版日期:
2020-02-10

文章信息/Info

Title:
Cryoablation with argon-helium knife for the treatment of advanced lung cancer: evaluation of its safety and effectiveness
作者:
周晴何瀚夫汪晟熊曙光
Author(s):
ZHOU Qing HE Hanfu WANG Sheng XIONG Shuguang.
Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, Sichuan Province 610051, China
关键词:
【关键词】 氩氦刀冷冻消融晚期肺癌疗效
文献标志码:
A
摘要:
【摘要】 目的?探讨CT引导下经皮穿刺氩氦刀冷冻消融治疗晚期肺癌的临床疗效及安全性。方法?回顾性分析氩氦刀冷冻消融治疗47例晚期肺癌患者,收集患者临床资料,术后观察患者的病灶变化、并发症,评价生活质量和体能状况,随访12、24和36个月,观察总生存(OS)率,评价远期疗效。结果?所有患者均顺利完成手术操作,无严重并发症发生。术后1个月,患者的生活质量和体能状况较术前明显改善(P< 0.05);术后3、6和12个月的客观有效率分别为66.0%、60.9%和51.2%,疾病控制率分别为93.6%、87.0%和75.6%。1、2、3年的生存率分别为85.1%、42.6%和27.6%。全组中位生存期为19.0个月(95%CI:18.3~24.6个月),中位疾病无进展生存期(mPFS)为8.9个月(95%CI:6.5~11.3个月)。结论?CT引导下经皮穿刺氩氦刀冷冻消融术是一种安全、有效的治疗晚期肺癌方法。

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备注/Memo

备注/Memo:
(收稿日期:2018-12-25)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2020-02-08