[1]陈佳佺,谢 辉,倪其泓,等.一站式治疗重症缺血性糖尿病足感染15例 [J].介入放射学杂志,2017,(07):647-650.
 CHEN Jiaquan,XIE Hui,NI Qihong,et al.One- station therapy for infected seriously- ischemic diabetic foot: initial experience in 15 patients[J].journal interventional radiology,2017,(07):647-650.
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一站式治疗重症缺血性糖尿病足感染15例 



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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2017年07期
页码:
647-650
栏目:
临床研究
出版日期:
2017-07-25

文章信息/Info

Title:
One- station therapy for infected seriously- ischemic diabetic foot: initial experience in 15 patients
作者:
陈佳佺 谢 辉 倪其泓 阚科佳 叶 猛 张 岚 郭相江
Author(s):
CHEN Jiaquan XIE Hui NI Qihong KAN Kejia YE Meng ZHANG Lan GUO Xiangjiang
Department of Vascular Surgery, Affiliated Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
关键词:
【关键词】 重症缺血 糖尿病足 感染 一站式治疗
文献标志码:
A
摘要:
【摘要】 目的 总结重症缺血性糖尿病足感染创面的一站式治疗经验。方法 回顾性分析2015年6月至2016年4月收治的15例重症缺血性糖尿病足坏疽患者(15条患肢)临床资料。对所有患者采用腔内修复术(EVR)开通闭塞段血管、手术清创及创面封闭负压引流(NPWT)、抗菌保湿伤口敷料进行一站式序贯治疗,评价感染创面愈合率及患肢保肢率。结果 15例患者中下肢动脉造影显示下肢多节段病变13例,单纯小腿病变2例;泛大西洋学会联盟(TASC)Ⅱ分级D级小腿动脉病变13条,C级病变2条。EVR术后,14条患肢至少开通1支小腿流出道;足底动脉环路(PPL)呈完整弓6例,半弓7例,无弓2例;清创后应用带自制冲洗设备NPWT,创面感染控制时间为(7.85±2.84) d。出院后每3~4 日随访,并以抗菌保湿的磺胺嘧啶银脂质水胶伤口敷料换药,结果显示创面愈合12例,平均愈合时间(3.70±0.87)个月,3例未愈合,其中2例小腿截肢(13.3%,足部均为PPL无弓),1例死于心血管事件;创面愈合组PPL病变情况与未愈合组比较,差异有显著统计学意义(P=0.006 7)。结论 重症缺血性糖尿病足感染治疗较复杂。EVR、带自制冲洗设备NPWT及抗菌保湿创面敷料一站式联合治疗,可作为首选方法有效增加患肢血供,缩短感染控制时间,降低截肢率。

参考文献/References:

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备注/Memo

备注/Memo:
(收稿日期:2017-03-08)
(本文编辑:边 佶)
更新日期/Last Update: 2017-07-12