[1]李虎子,贾英杰,孔凡铭,等.改良RECIST标准更适用经TACE治疗的肝癌患者的预后评价[J].介入放射学杂志,2016,(01):29-33.
　LI Hu- zi,JIA Ying- jie,KONG Fan- ming,et al.Evaluation of modified RECIST criteria in predicting the prognosis of HCC patients treated with TACE[J].journal interventional radiology,2016,(01):29-33.
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改良RECIST标准更适用经TACE治疗的肝癌患者的预后评价 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2016年01期
页码:
29-33
栏目:
肿瘤介入
出版日期:
2016-01-25

文章信息/Info

Title:
Evaluation of modified RECIST criteria in predicting the prognosis of HCC patients treated with TACE
作者:
李虎子;  贾英杰;  孔凡铭;  方文岩;  赵 成;  姜付显
Author(s):
LI Hu- zi;  JIA Ying- jie;  KONG Fan- ming;  FANG Wen- yan;  ZHAO Cheng;  JIANG Fu- xian
Department of Oncology， First Teaching Hospital of Tianjin University of Traditional Chinese Medicine， Tianjin 300193， China
关键词:
【关键词】 肝癌;  疗效评价;  选择性肝动脉栓塞
文献标志码:
A
摘要:
【摘要】 目的 本研究拟确定采用哪一种短期疗效评价标准能够客观、有效、准确地预测经TACE治疗的肝癌患者的预后。方法 回顾性分析59例行TACE治疗的肝癌患者，收集治疗前及治疗后1个月的增强CT或增强MRI影像学资料。分别依据RECIST 1.1标准和mRECIST标准行短期疗效评价，分析两种标准评价结果的一致性；然后依据不同的评价结果，将所有患者分为有效组和无效组，分别分析两组患者中位生存时间和2年生存率的差异。结果 对所有患者进行短期疗效评价，依据RECIST 1.1标准评价为CR、PR、SD、PD的患者；依据mRECIST标准评价为CR、PR、SD、PD的患者；两种标准内部一致性极差（κ=0.19，95%CI，0.16~0.26）。依据RECIST 1.1标准，有效组和无效组患者中位生存时间分别为25个月和20个月，2年生存率分别为62%和80%，两组差异无统计学意义（P>0.05）；依据mRECIST标准，有效组和无效组患者中位生存时间分别为25个月和14个月，2年生存率分别为84%和68%，两组差异有显著统计学意义（P<0.001）。多因素分析，mRECIST标准评价结果是预后的独立预测因素（P=0.02）。结论 采用mRECIST标准评价经TACE治疗的肝癌患者较RECIST标准更有优势。

参考文献/References:

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备注/Memo

备注/Memo:
（收稿日期：２０１5-０6-24）
（本文编辑：俞瑞纲）
更新日期/Last Update: 2016-01-22