[1]顾佳宁,姜伟峰,周 立,等.瑞舒伐他汀对持续性心房颤动导管消融术后早期复发的影响[J].介入放射学杂志,2014,(10):848-852.
　GU Jia ning,JIANG Wei feng,ZHOU Li,et al.Evaluation of rosuvastatin in preventing early recurrence of persistent atrial fibrillation after catheter ablation treatment[J].journal interventional radiology,2014,(10):848-852.
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瑞舒伐他汀对持续性心房颤动导管消融术后早期复发的影响 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年10期
页码:
848-852
栏目:
心脏介入
出版日期:
2014-10-25

文章信息/Info

Title:
Evaluation of rosuvastatin in preventing early recurrence of persistent atrial fibrillation after catheter ablation treatment
作者:
顾佳宁;  姜伟峰;  周 立;  张瑞岩
Author(s):
GU Jia ning;  JIANG Wei feng;  ZHOU Li;  ZHANG Rui yan.
Department of Cardiology， Affiliated Ruijin Hospital， School of Medicine， Jiaotong University， Shanghai 200025， China
关键词:
【关键词】 心房颤动;  导管消融;  瑞舒伐他汀;  炎症
文献标志码:
A
摘要:
【摘要】 目的 探讨瑞舒伐他汀对消融术后早期炎性反应及术后早期复发的影响。方法 连续入选84例拟行导管消融术的持续性心房颤动（房颤）患者，随机分为两组：A组42例给予瑞舒伐他汀10 mg/d； B组42例为空白对照组。随访术后1个月患者的血脂水平、血清高敏C反应蛋白（hs CRP）、白细胞介素-6（IL 6）以及患者消融术后1个月内的复发率。比较消融术前、术后以及两组间炎性指标变化及其与术后早期复发的关系。结果 消融术后1个月时，A组的hs CRP及IL 6水平显著低于B组，且明显低于治疗前；而B组hs CRP及IL 6水平较术前显著增高。术后1个月，A组和B组分别有29例和25例患者成功维持窦性心律（P = 0.362）；进一步将A组分为未复发组和复发组，未复发组的炎性指标降低幅度较大，但差异无统计学意义。结论 消融术后早期存在显著的炎性反应。瑞舒伐他汀虽能有效降低炎性反应，但仅有减少术后早期复发的趋势。炎症指标降低越多房颤复发率越低，但差异无统计学意义。 

参考文献/References:

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备注/Memo

备注/Memo:
（收稿日期：２０１4-０4-０7）
（本文编辑：李 欣
更新日期/Last Update: 2014-10-21