[1]姚红响,陈根生,叶冠雄,等.胆道支架联合125I粒子条治疗恶性梗阻性黄疸[J].介入放射学杂志,2014,(10):893-896.
 YAO Hong xiang,CHEN Gen sheng,YE Guan xiong,et al.Biliary stenting combined with 125I seed implantation intracavitary irradiation for the treatment of malignant obstructive jaundice[J].journal interventional radiology,2014,(10):893-896.
点击复制

胆道支架联合125I粒子条治疗恶性梗阻性黄疸 ()

PDF下载中关闭

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年10期
页码:
893-896
栏目:
非血管介入
出版日期:
2014-10-25

文章信息/Info

Title:
Biliary stenting combined with 125I seed implantation intracavitary irradiation for the treatment of malignant obstructive jaundice
作者:
姚红响;  陈根生;  叶冠雄;  徐胜前;  吴成军;  秦 勇;  潘德标;  曾 群; 陈 烨;  张鹏朝
Author(s):
YAO Hong xiang;  CHEN Gen sheng;  YE Guan xiong;  XU Sheng qian;  WU Cheng jun;  QIN Yong;  PAN De biao;  ZENG Qun;  CHEN Ye;  ZHANG Peng zhao.
Department of Interventional Radiology, Lishui Municipal People’s Hospital, Lishui, Zhejiang Province 323000, China
关键词:
【关键词】 胆道支架;  125I粒子;  腔内照射;  恶性梗阻性黄疸
文献标志码:
A
摘要:
【摘要】 目的 探讨通过胆道支架联合125I粒子条植入腔内照射治疗恶性梗阻性黄疸技术方法、安全性及临床价值。方法 对36例恶性阻塞性黄疸患者,先行PTCD引流后,二期采用125I粒子条联合胆道支架植入腔内照射治疗恶性梗阻性黄疸。结果 手术过程支架及粒子条移位2例,经胆道活检钳复位,技术成功率100%,黄疸缓解率100%;所有患者术后随访1 ~ 23个月,未发生放射性泄漏、放射性肠炎等并发症;支架内未见明显肿瘤复发导致再次梗阻征象,但部分患者(25%)由于支架网孔处内膜增生或胆道内结石形成导致肝内胆管轻度扩张;其中位生存时间10.9个月。结论 125I粒子条联合胆道支架植入腔内照射治疗恶性梗阻性黄疸手术安全可靠,疗效肯定,术后能延长支架通畅时间,有望延长患者生存期。 

参考文献/References:

[1] 夏 宁, 程永德, 王忠敏, 等. 胆道支架再狭窄的介入治疗进展[J]. 介入放射学杂志, 2014, 23: 82 85.
[2] Rossi P, Bezzl M, Rossi M, et al. Metallic stents in malignant biliary obstruction: Res ults of multicenter European study of 240 patients[Z], 1994: 279.
[3] 常 钢, 游 洋, 孟凡喆, 等. 恶性梗阻性黄疸治疗探讨: 胆道支架置入 + 碘-125粒子腔内照射联合治疗[J]. 中国医学影像技术, 2007, 23: 439 441.
[4] 戴真煜, 姚立正, 李文会, 等. 经皮胆道支架联合支架旁~(125)Ⅰ粒子条植入治疗恶性胆道梗阻[J]. 介入放射学杂志, 2011, 20: 706 708.
[5] 张金山. 现代腹部介入放射学[M]. 北京: 科学出版社, 2000: 318.
[6] 陈 旭, 朱光宇, 滕皋军, 等. 胆管内照射支架应用的实验研究[J]. 介入放射学杂志, 2012, 21: 399 404.
[7] Nag S, Dehaan M, Scruggs GR, et al. Long term Follow Up of patients of intrahepatic malignancies treated with iodine 125 brachytherapy[J]. Int J Radiat Oncol Biol Phys, 2005, 63, Supplement 1: S281.
[8] 李 说, 颜志平, 张 雯, 等. 兔门静脉主干内植入连续排列125I粒子条的实验研究[J]. 介入放射学杂志, 2009, 18: 607 611.
[9] Liu Y, Liu JL, Cai ZZ, et al. A novel approach for treatment of unresectable extrahepatic bile duct carcinoma: design of radioactive stents and an experimental trial in healthy pigs[J]. Gastrointest Endosc, 2009, 69: 517 524.
[10]樊 超, 翟 超, 吕 毅, 等. 胆道可吸收支架的体内实验研究[J]. 生物医学工程学杂志, 2011, 28: 763 767.
[11]郭金和, 朱光宇, 朱海东, 等. 胆管内照射支架的研制及临床应用的初步结果[J]. 中华医学杂志, 2011, 91: 2310 2313.
[12]姚红响, 陈根生, 徐 磊, 等. CT引导下同轴法125I粒子植入治疗腹膜后淋巴结转移瘤21例[J]. 介入放射学杂志, 2014, 23: 42 45.

相似文献/References:

[1]朱永强,陈俊英,郭剑峰.CT引导下125I粒子植入治疗晚期胰腺癌的临床疗效分析[J].介入放射学杂志,2011,(04):283.
 ZHU Yong-qiang,CHEN Jun-ying,GUO Jian-feng.CT-guided 125I seed implantation for the treatment of advanced pancreatic carcinoma: a clinical therapeutic analysis[J].journal interventional radiology,2011,(10):283.
[2]宋 琦,刘 玉,胡曙东,等.磁共振弥散加权成像在125I粒子组织间植入治疗胰腺癌疗效评估中的应用[J].介入放射学杂志,2012,(06):492.
 SONG Qi,LIU Yu,HU Shu-dong,et al. The application of MR diffusion-weighted imaging in evaluating the efficacy of 125I seed interstitial brachytherapy for pancreatic carcinomas: an experimental study in vivo[J].journal interventional radiology,2012,(10):492.
[3]彭晶晶,谭 勇,谭 艳,等. 125I粒子植入治疗结肠直肠癌肝转移[J].介入放射学杂志,2012,(09):773.
 PENG Jing- jing,TAN Yong,TAN- Yan,et al. Interstitial implantation of 125I seeds for the treatment of colorectal liver metastases[J].journal interventional radiology,2012,(10):773.
[4]吴伟经,郭金和. 恶性胆管梗阻内照射支架植入术的护理体会[J].介入放射学杂志,2012,(09):787.
 WU Wei- jing,GUO Jin- he.. Malignant bile duct obstruction treated with intraluminal irradiation stent implantation: clinical nursing experience[J].journal interventional radiology,2012,(10):787.
[5]蒋 奡,王忠敏,张丽云,等. 125I粒子持续照射对Sw1990及Panc?蛳 1细胞 生物学效应的影响[J].介入放射学杂志,2013,(06):490.
 JIANG Ao,WANG Zhong? min,ZHANG Li? yun,et al. The biological effects of continuous 125I seeds irradiation on sw1990 and panc?蛳 1 cells: a comparison study[J].journal interventional radiology,2013,(10):490.
[6]张炜浩,郭 志,李保国,等.CT导向下125I粒子植入补救治疗盆腔恶性肿瘤近期疗效评价[J].介入放射学杂志,2013,(04):308.
 ZHANG Wei? hao,GUO Zhi,LI Bao? guo,et al.CT- guided radioactive seeds 125I implantation used as salvage therapy for malignant pelvic tumors: evaluation of short- term effects[J].journal interventional radiology,2013,(10):308.
[7]黄兢姚,杨维竹,江 娜,等.125I粒子条胆道支架治疗恶性胆道梗阻38例[J].介入放射学杂志,2014,(07):633.
 HUANG Jing- yao,YANG Wei- zhu,JIANG Na,et al.Percutaneous implantation of 125I seed- strip combined with biliary stent for the treatment of malignant biliary obstruction: analysis of 38 cases[J].journal interventional radiology,2014,(10):633.
[8]刘 岩,刘瑞宝,王 平,等. 经导管植入125I放射性粒子治疗肝癌伴门静脉癌栓19例[J].介入放射学杂志,2014,(01):35.
 LIU Yan,LIU Rui? bao,WANG Ping,et al. Percutaneous transcatheter implantation of 125iodine seeds for the treatment of liver cancer associated with portal vein tumor thrombus: initial experience in 19 cases[J].journal interventional radiology,2014,(10):35.
[9]张炜浩,郭 志,邢文阁,等. CT导向下125I粒子植入挽救治疗肾上腺转移瘤11例近期疗效评价[J].介入放射学杂志,2013,(10):815.
 ZHANG Wei? hao,GUO Zhi,XING Wen? ge,et al. CT?蛳 guided radioactive 125I seeds implantation as a salvage therapy for adrenal metastases: evaluation of short?蛳 term effect in 11 cases[J].journal interventional radiology,2013,(10):815.
[10]蔡 霞,陈 坚,李青荷,等. 胆道支架联合支架旁125I粒子条植入的护理体会[J].介入放射学杂志,2013,(10):865.
 CAI Xia,CHEN Jian,LI Qing? he,et al. Nursing experience with patients receiving biliary stenting combined with linear 125I seeds strand implantation for inoperable malignant biliary obstruction[J].journal interventional radiology,2013,(10):865.
[11]诸葛英,姚红响,曾 群.胆道支架联合125I粒子条治疗恶性梗阻性黄疸的护理[J].介入放射学杂志,2015,(05):449.
 ZHU Ge ying,YAO Hong xiang,ZENG Qun.Nursing care for patients with malignant obstructive jaundice receiving biliary stenting combined with linear 125I seeds strand implantation[J].journal interventional radiology,2015,(10):449.

备注/Memo

备注/Memo:
(收稿日期:2014-02-17)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2014-10-22