[1]李 鑫,梁 萍,于晓玲,等.经皮微波消融肾细胞癌疗效的超声造影评价[J].介入放射学杂志,2014,(08):688-692.
　LI Xin,LIANG Ping,YU Xiao ling,et al.Percutaneous microwave ablation for renal cell carcinoma： evaluation of therapeutic effect with contrast enhanced ultrasound[J].journal interventional radiology,2014,(08):688-692.
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经皮微波消融肾细胞癌疗效的超声造影评价 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年08期
页码:
688-692
栏目:
非血管介入
出版日期:
2014-08-25

文章信息/Info

Title:
Percutaneous microwave ablation for renal cell carcinoma： evaluation of therapeutic effect with contrast enhanced ultrasound
作者:
 李 鑫;  梁 萍;  于晓玲;  于 杰;  程志刚;  韩志宇;  刘方义;  穆梦娟;  陈超男
Author(s):
LI Xin;  LIANG Ping;  YU Xiao ling;  YU Jie;  CHENG Zhi gang;  HAN Zhi yu;  LIU Fang yi;  MU Meng juan;  CHEN Chao nan.
Department of Interventional Ultrasound， General Hospital of PLA， Beijing 100853， China
关键词:
【关键词】 超声造影;  微波消融;  肾细胞癌
文献标志码:
A
摘要:
【摘要】 目的 探讨低机械指数灰阶超声造影（CEUS）评估经皮微波消融肾细胞癌临床疗效的可行性与准确性。方法 2006年3月—2013年7月，105例肾细胞癌患者109个病灶，平均直径（3.1 ± 1.3）cm行超声引导下经皮微波消融治疗。消融后3 ｄ，CEUS对消融区检查结果与同期增强CT/MRI及穿刺活检病理结果进行比较，对近期消融疗效进行评估；随后 1、3和6个月及之后每6个月进行CEUS和CT/ MRI检查，对远期消融疗效进行评估。结果 微波消融后3 d，CEUS检查显示94个（94/109，86.2％）病灶呈完全消融状态，15个（15/109，13.8％）病灶有残癌。其中，13个（13/15，86.7％）残癌病灶由同期增强CT/MRI检查或活检病理证实。CEUS对微波消融肾癌近期疗效评价的灵敏度、特异度、准确性、阳性预测值和阴性预测值分别为100％、97.9％、98.2％、86.7％和100％。在3 ~ 90个月（中位24.6个月）的随访期内，CEUS检查显示有7例复发（1例肾实质内、2例外凸靠近肠道及4例内凸靠近肾盂），其中6例与同期CT/MRI检查相一致，CEUS对消融区的远期疗效评价的灵敏度、特异度、准确性、阳性预测值和阴性预测值分别为85.7％、99.0％、98.2％、85.7％和99.0％。结论 实时灰阶CEUS在评估经皮微波消融肾细胞癌疗效方面具有灵敏、准确、便捷的应用价值。

参考文献/References:

［1］ Liang P， Wang Y， Zhang D， et al. Ultrasound guided percutaneous microwave ablation for small renal cancer： initial experience［J］. J Urol， 2008， 180： 844 848.
［2］ Schmit GD， Thompson RH， Kurup AN， et al. Percutaneous cryoablation of solitary sporadic renal cell carcinomas［J］. BJU Int， 2012， 110： E526 531.
［3］ Adeyanju OO， Al Angari HM， Sahakian AV. The optimization of needle electrode number and placement for irreversible electroporation of hepatocellular carcinoma［J］. Radiol Oncol， 2012， 46： 126 135.
［4］ Yu J， Liang P， Yu XL， et al. US guided percutaneous microwave ablation of renal cell carcinoma： intermediate term results［J］. Radiology， 2012， 263： 900 908.
［5］ Frieser M， Kiesel J， Lindner A， et al. Efficacy of contrast enhanced US versus CT or MRI for the therapeutic control of percutaneous radiofrequency ablation in the case of hepatic malignancies［J］. Ultraschall Med， 2011， 32： 148 153.
［6］ Inoue T， Kudo M， Hatanaka K， et al. Usefulness of contrast enhanced ultrasonography to evaluate the post treatment responses of radiofrequency ablation for hepatocellular carcinoma： comparison with dynamic CT［J］. Oncology， 2013， 84： 51 57.
［7］ Qu P， Yu X， Liang P， et al. Contrast enhanced ultrasound in the characterization of hepatocellular carcinomas treated by ablation： comparison with contrast enhanced magnetic resonance imaging［J］. Ultrasound Med Biol， 2013， 39： 1571 1579.
［8］ Li X， Liang P， Guo M， et al. Real time contrast enhanced ultrasound in diagnosis of solid renal lesions［J］. Discov Med， 2013， 16： 15 25.
［9］ Zhao X， Wang W， Zhang S， et al. Improved outcome of percutaneous radiofrequency ablation in renal cell carcinoma： a retrospective study of intraoperative contrast enhanced ultrasonography in 73 patients［J］. Abdom Imaging， 2012， 37： 885 891.
［10］ Hoeffel C， Pousset M， Timsit MO， et al. Radiofrequency ablation of renal tumours： diagnostic accuracy of contrast enhanced ultrasound for early detection of residual tumour［J］. Eur Radiol， 2010， 20： 1812 1821.
［11］ Barwari K， Wijkstra H， Van Delden OM， et al. Contrast enhanced ultrasound for the evaluation of the cryolesion after laparoscopic renal cryoablation： an initial report［J］. J Endourol， 2013， 27： 402 407.
［12］ Kong WT， Zhang WW， Guo HQ， et al. Application of contrast enhanced ultrasonography after radiofrequency ablation for renal cell carcinoma： is it sufficient for assessment of therapeutic response？［J］. Abdom Imaging， 2011， 36： 342 347.
［13］ Meloni MF， Bertolotto M， Alberzoni C， et al. Follow up after percutaneous radiofrequency ablation of renal cell carcinoma： contrast enhanced sonography versus contrast enhanced CT or MRI［J］. AJR， 2008， 191： 1233 1238.
［14］ Park SY， Kim CK， Park BK. Dual energy CT in assessing therapeutic response to radiofrequency ablation of renal cell carcinomas［J］. Eur J Radiol， 2014， 83： e73 79.

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备注/Memo

备注/Memo:
（收稿日期：２０１3-1０-16）
（本文编辑：俞瑞纲）
更新日期/Last Update: 2014-08-22