[1]茹利新,张海兵,许建伟,等.经皮经肝胆管引流支架植入联合三维适形放射治疗恶性梗阻性黄疸48例分析[J].介入放射学杂志,2012,(05):395-398.
 ,,et al. Threedimensional conformal radiotherapy combined with PTCD and PTBS for the treatment of malignant obstructive jaundice: a clinical analysis of 48 cases[J].journal interventional radiology,2012,(05):395-398.
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经皮经肝胆管引流支架植入联合三维适形放射治疗恶性梗阻性黄疸48例分析 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2012年05期
页码:
395-398
栏目:
非血管介入
出版日期:
2012-05-30

文章信息/Info

Title:
 Threedimensional conformal radiotherapy combined with PTCD and PTBS for the treatment of malignant obstructive jaundice: a clinical analysis of 48 cases
作者:
 茹利新 张海兵 许建伟 纪鹏天 郑少俊
Author(s):
 RU Lixin ZHANG Haibing XU Jianwei JI Pengtian ZHENG Shaojun.
 Department of Interventional Radiotherapy, Huzhou Central Hospital, Huzhou, Zhejiang province 313000, China
关键词:
 【关键词】   恶性梗阻性黄疸 经皮肝穿刺胆管引流 胆管内支架置入术 三维适形放射治疗
文献标志码:
A
摘要:
 【摘要】 目的 观察经皮肝胆管穿刺引流(PTCD)及胆管内支架置入术(PTBS)联合三维适形放疗(3DCRT)治疗恶性梗阻性黄疸的疗效及应用价值。方法   对48例恶性梗阻性黄疸患者行经皮肝胆管穿刺置管引流及胆管内支架植入,术后予3DCRT,常规分割,总剂量DT 40 ~ 60 Gy/4 ~ 6周,观察近期疗效及生存率。结果   48例均引流成功,术前血清总胆红素(221.85 ± 54.73) μmol/L,术后1、2及3周总胆红素分别下降为(129.68 ± 23.58)、(88.29 ± 15.70) 和(48.58 ± 11.61) μmol/L;经3DCRT后肿瘤完全缓解3例,部分缓解36例,稳定9例,肿瘤总有效率81.3%;1、2年累积生存率分别是77.1%、37.5%;中位生存期18.5个月;无治疗相关的严重并发症。结论   PTBD + 支架植入联合3DCRT治疗恶性梗阻性黄疸是一种安全、有效的姑息性治疗方法,可以改善恶性肿瘤伴黄疸患者的临床症状,提高生存质量并延长生存时间。

参考文献/References:

[1]   Bjrnsson E, Gustafsson J, Borkman J, et al. Fate of patients with obstructive jaundice[J]. J Hosp Med, 2008, 3: 117  123.
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[9] 丁广成, 朱晓民, 秦德华. 经皮肝穿胆汁引流联合三维适形放射治疗肝门部胆管癌疗效分析[J]. 肿瘤研究与临床, 2006: 631  632.

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备注/Memo

备注/Memo:
 (收稿日期:20120209)
更新日期/Last Update: