[1]冯耀良,赵林波,王学浩,等.中晚期肝癌肝移植术前介入治疗的临床价值[J].介入放射学杂志,2007,(07):464.
FENG Yao-liang ZHAO Lin-bo WANG Xue-hao ZHANG Feng KONG Lian-bao LI Xiang-cheng SHI Hai-bin WANG Jie LIU Sheng.Clinical evaluation of interventional therapy in patients with advanced hepatocellular carcinoma before transplantation[J].journal interventional radiology,2007,(07):464.
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中晚期肝癌肝移植术前介入治疗的临床价值()
《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]
- 卷:
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- 期数:
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2007年07期
- 页码:
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464
- 栏目:
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肿瘤介入
- 出版日期:
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2007-07-15
文章信息/Info
- Title:
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Clinical evaluation of interventional therapy in patients with advanced hepatocellular carcinoma before transplantation
- 作者:
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冯耀良; 赵林波; 王学浩; 等
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冯耀良,赵林波,施海彬,王杰,刘圣,FENG Yao-liang,ZHAO Lin-bo,SHI Hai-bin,WANG Jie,LIU Sheng(210029,南京医科大学附属第一医院介入放射科)
王学浩,张峰,孔连宝,李相成,WANG Xue-hao,ZHANG Feng,KONG Lian-bao,LI Xiang-cheng(210029,南京医科大学附属第一医院肝移植中心)
- Author(s):
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FENG Yao-liang ZHAO Lin-bo WANG Xue-hao ZHANG Feng KONG Lian-bao LI Xiang-cheng SHI Hai-bin WANG Jie LIU Sheng
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- 关键词:
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肝细胞性肝癌 肝移植 介入治疗 生存率
- 分类号:
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R735.7
- 文献标志码:
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A
- 摘要:
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目的 探讨中晚期肝癌(HCC)肝移植术前介入治疗对预防肝移植后肝癌复发及提高患者生存率的临床价值.方法 回顾分析2004年1月至2005年11月我院接受肝移植的40例中晚期HCC患者的临床资料,其中加例(介入组)术前辅以介入治疗,另外20例作为同期对照组(未介入组),比较两组的累计生存率和无瘤生存率,并观察介入治疗的安全性及不良反应.结果 经统计学分析,介入组和未介入组1、2年无瘤生存率分别为70%、55%和45%、30%,两组累计无瘤生存率比较差异有统计学意义(P<0.05);介入组1、2年生存率(80%、60%)亦高于未介入组(55%、35%),两组术后累计生存率比较差异有统计学意义(P<0.05).介入组患者均未出现与介入治疗相关的肝、肾毒性或影响移植手术的血管性病变.结论 移植前辅以介入治疗可显著提高中晚期HCC术后生存率.
参考文献/References:
1.Yu AS.Keeffe EB Management of hepatocellular carcinoma 2003
2.Qian J.Feng GS.Vogl T Combined interventional therapy of hepatocellular carcinoma [期刊论文] -World Journal of Gastroenterology2003
3.Yu ZP.Zhang QY The status and role of hepatic ehemoembolization in the surgical treatment of HCC 2003
4.Jonas S.Steinmuller T.Settmacher U Liver transplantation for recurrent hepatocellular carcinoma in Europe 2001
5.Graziadei IW.Sandmueller H.Waldenberger P Chemoembolization followed by liver transplantation for hepatocellular carcinoma impedes tumor progression while on the waiting list and leads to excellent outcome 2003
6.Suehiro T.Terashi T.Shiotani S Liver transplantation for hepatocellular carcinoma 2002(01)
7.Roayaie S.Frischer JS.Emre SH Long-term results with multimodal adjuvant therapy and liver transplantation for the treatment of hepatocellular carcinoma larger than 5 centimeters 2002
8.Harnois DM.Steers J.Andrews JC Preoperative hepatic chemoembolization followed by orthotopic liver transplantation for hepatocellular carcinoma 1999
9.Molmenti EP.Klintmalm GB Hepatocellular carcinoma in liver transplantation 2001
10.Xiao BX The progresses in the treatment of hepatocellular carcinoma 2003
11.Huang JF The role and evaluation of liver transplantation in the treatment of HCC 2001
更新日期/Last Update:
2007-07-15