[1]史跃,高从敬,董生良,等.细胞因子诱导杀伤细胞灌注治疗原发性肝癌临床应用[J].介入放射学杂志,2007,(04):235.
　SHI Yue,GAO Cong-jing,DONG Sheng-liang,et al.Cytokine-induced killer cell for interventional chemotherapy of hepatocellular carcinoma[J].journal interventional radiology,2007,(04):235.
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细胞因子诱导杀伤细胞灌注治疗原发性肝癌临床应用()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2007年04期
页码:
235
栏目:
肿瘤介入
出版日期:
2007-04-15

文章信息/Info

Title:
Cytokine-induced killer cell for interventional chemotherapy of hepatocellular carcinoma
作者:
史跃; 高从敬; 董生良; 等
２２１００４江苏徐州解放军第九七医院放射科（史跃、高从敬），实验科（陈复兴），肿瘤科（徐永茂）；江苏宿迁中医院（董生良）
Author(s):
SHI Yue; GAO Cong-jing; DONG Sheng-liang; ChEN Fu-xing; XU Yong-mao
Department of Radiology，The９７th Hospital of PLA，Xuzhou２２１００４，China
关键词:
肝癌; 细胞因子诱导的杀伤细胞; 介入治疗; 随访
分类号:
R６５７.３２
文献标志码:
A
摘要:
目的探讨肝动脉细胞因子诱导杀伤细胞（CIK细胞）灌注＋超液化碘油栓塞治疗原发性肝癌的疗效。方法采用超选择段性肝动脉灌注CIK细胞＋超液化碘油栓塞治疗原发性肝癌及经皮肝穿刺瘤体内多点注射CIK细胞共３８例（研究组）；将同期采用常规剂量经肝动脉段性化疗栓塞（C-TACE）联合经皮肝瘤体内注入无水乙醇８０例（双介入组）；单纯经皮肝动脉常规剂量C-TACE１３４例（单纯组）相比较。结果研究组、双介入组和单纯组近期显效率分别为７６．３％、４１．３％和１４．９％，研究组的AFP降至正常及明显下降率则显著高于双介入组和单纯组，３组血清AFP变化差异有统计学意义（P＜０．０１）。结论采用超选择段性肝动脉灌注CIK细胞＋超液化碘油栓塞综合治疗原发性肝癌，可以提高患者的免疫功能、生存质量，延长带瘤生存期。

参考文献/References:

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［８］Tarazov PG，Polysalov VN，Prozorovskij KV，et al．Ischemic complications of transcatheter arterial chemoembolization in liver malignancies［J］．Acta Radiol，２０００，４１：１５６-１６０．

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备注/Memo

备注/Memo:
收稿日期：２００５-１１-２１
更新日期/Last Update: 2007-04-15