[1]罗望池,李贵福,李铁林,等.Wingspan支架治疗症状性颅内动脉狭窄的疗效及随访[J].介入放射学杂志,2011,(07):513.
 LUO Wang-chi,LI Gui-fu,LI Tie-lin,et al.Treatment of symptomatic intracranial arterial stenosis with Wingspan stent system[J].journal interventional radiology,2011,(07):513.
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Wingspan支架治疗症状性颅内动脉狭窄的疗效及随访()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2011年07期
页码:
513
栏目:
神经介入
出版日期:
2011-07-30

文章信息/Info

Title:
Treatment of symptomatic intracranial arterial stenosis with Wingspan stent system
作者:
罗望池 李贵福 李铁林 朱吉祥 尤劲松 马朝晖 黄 燕
510120 广州中医药大学附属广东省中医院脑血管病中心脑病三科
Author(s):

LUO Wang-chi LI Gui-fu LI Tie-lin ZHU Ji-xiang YOU Jing-song MA Zhao-hui HUANG Yan.

Department of Neurovascular Surgery, Center of Cerebrovascular Diseases, Guangdong Provincial Traditional Chinese Medicine Hospital, Guangzhou 510120, China

关键词:
血管成形术 症状性颅内动脉狭窄 支架
分类号:
R743.4
文献标志码:
A
摘要:
目的   观察GatewayWingspan支架系统治疗症状性颅内动脉狭窄的安全性,以及防治再次脑卒中的疗效。方法 应用GatewayWingspan支架系统治疗药物治疗无效的症状性颅内动脉狭窄患者36例(38处),其中择期手术32例,急诊手术4例。38处狭窄中22处位于后循环,16处位于前循环。结果 术前平均狭窄程度为72.6% ± 12.6%, Gateway球囊扩张后残余狭窄33.8% ± 15.2%,Wingspan支架置入后残余狭窄23.6% ± 13.9%,治疗成功率为97.4%。4例发生围手术期并发症,其中择期手术置入支架32例,有2例发生并发症,急诊支架置入4例,有2例发生并发症。择期手术穿支动脉闭塞1例,导丝穿破大脑中动脉破裂出血1例;急诊手术支架内急性血栓形成2例,1例在介入术中发生,1例在支架置入后24 h发生。并发症发生率为11.1%(4/36)。1个月内再发同侧卒中2例,占5.5%(2/36)。在1 ~ 24个月(平均9.6个月)的随访中,30 d内脑卒中和31 d ~ 1年同侧脑卒中的发生率为11.1%(4/36)。DSA复查10例,2例出现再狭窄,均位于大脑中动脉。结论 GatewayWingspan支架系统治疗症状性颅内动脉狭窄有较好的安全性和短期临床疗效,其长期疗效还需更大量样本及更长时间的随访研究,如何防治支架术后再狭窄需进一步的研究。

参考文献/References:

[1] Bose A, Hartmann M, Henkes H, et al. A novel, self-expand-ing, nitinol stent in medically refractory intracranial atheroscle-rotic stenoses: the Wingspan study[J]. Stroke, 2007, 38: 1531 - 1537.
[2] Fiorella D, Levy EI, Turk AS, et al. US multicenter experience with the wingspan stent system for the treatment of intracranial atheromatous disease periprocedural results [J]. Stroke, 2007, 38: 881 - 887.
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[7] Wolfe TJ, Fitzsimmons BF, Hussain SI, et al. Long term clinical and angiographic outcomes with the Wingspan stent for treatment of symptomatic 50 - 99% intracranial atherosclerosis: single center experience in 51 cases[J]. J Neurointerv Surg, 2009, 1: 40 - 43.v [8] Zaidat OO, Klucznik R, Alexander MJ, et al. The NIH registry on use of the Wingspan stent for symptomatic 70 - 99% intracranial arterial stenosis[J]. Neurology, 2008, 70: 1518 - 1524.
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备注/Memo

备注/Memo:
收稿日期:20101024
更新日期/Last Update: 2011-07-30