[1]李子川,杨军,耿树军,等.老年患者急性下肢动脉缺血介入溶栓及支架置入治疗[J].介入放射学杂志,2010,(08):651-654.
 LI Zichuan,YANG Jun,GENG Sujun,et al.The interventional intra-arterial thrombolysis of acute ischemia of lower limb in elderly patients[J].journal interventional radiology,2010,(08):651-654.
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老年患者急性下肢动脉缺血介入溶栓及支架置入治疗()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2010年08期
页码:
651-654
栏目:
临床研究
出版日期:
2010-08-15

文章信息/Info

Title:
The interventional intra-arterial thrombolysis of acute ischemia of lower limb in elderly patients
作者:
李子川杨军耿树军
100053中国中医科学院广安门医院放射科(李子川、汪平);外科(杨军、耿树军、莫爵飞、杨超波)
Author(s):
LI Zi-chuanYANG JunGENG Su-junMO Jue-feiYANG Chao-boWANG Ping.
Guanganmen Hospital,Academy of Traditional Chinese Medical Sciences,Beijing100053,China
关键词:
急性下肢缺血导管溶栓血管成形术
分类号:
R654.3
文献标志码:
B
摘要:
目的探讨介入溶栓治疗对老年急性下肢动脉缺血治疗的疗效和安全性。方法回顾性总结2007年9月-2009年3月通过介入溶栓方法治疗的18例老年下肢动脉缺血患者治疗方式的选择、介入治疗过程中及介入治疗后发生合并症、并发症的处理,分析总结介入溶栓治疗对老年急性下肢动脉缺血治疗的疗效和安全性。结果本组患者从下肢缺血症状出现到明确诊断时间为4h~12d;患者多合并有多系统慢性病。采用动脉内导管溶栓治疗1~3d,溶栓治疗后对残余病变行腔内成形术及支架置入。15例治疗过程中分别出现出血、术后发热、肢体再灌注损伤、肺栓塞等。经治疗,3例患者行1~3趾经跖骨截趾术,14例患者保肢成功;1例患者动脉开通后2d,因再灌注损伤致多脏器功能衰竭死亡。结论介入溶栓治疗对老年急性下肢动脉缺血的治疗安全、有效,对此类患者可优先考虑。

参考文献/References:

[1]Henke PK.Contemporary management of acute limb ischemia:factors associated with amputation and in-hospital mortality[J].Semin Vasc Surg,2009,22:34-40.
[2]Schumann R,Rieger J,Ludwig M.Acute peripheral arterial occlusive disease[J].Med Klin(Munich),2007,102:457-471.
[3]Earnshaw JJ,Whitman B,Foy C.National audit of thrombolysis for acute leg ischemia(NATALI ):clinical factors associated with early outcome [J].J Vasc Surg,2004,39:1018-1025.
[4]Comerota AJ ,Gravett MH.Do randomized trials of thrombolysis versus open revascularization still apply to current management :what has changed﹖[J]Semin Vasc Surg,2009,22:41-46.
[5]Weinrich M,Justinger C,Khler MF ,et al.Intraarterial thrombolysis in acute limb ischemia:alternative treatment and basic principles of further interventions[J].Zentralbl Chir,2008,133:355-358.
[6]Beyersdorf F,Schlensak C.Controlled reperfusion after acute and persistent limb ischemia[J].Semin Vasc Surg,2009,22:52-57.
[7]Yassin MM,Harkin DW,Barros D,et al.Lower limb ischemia-reperfusion injury triggers a systemic inflammatory response and multiple organ dysfunction[J].World J Surg,2002,26:115-121.
[8]Parmar JH,Aslam M,Standfield NJ.Percutaneous transluminal angioplasty of lower limb arteries causes a systemic inflammatory response[J].Ann Vasc Surg,2009,23:569-576.

相似文献/References:

[1]司同国,郭志.近期脑栓塞患者下肢动脉栓塞的溶栓治疗[J].介入放射学杂志,2008,(05):359.
 SI Tongguo,GUO Zhi.Thrombolysis for acute lower limb arterial embolism in patients with recent cerebral embolism[J].journal interventional radiology,2008,(08):359.
[2]薛冠华,梁卫,黄晓钟,等.导管溶栓治疗急性下肢动脉缺血的疗效评价[J].介入放射学杂志,2010,(09):715.
 XUE Guanhua,LIANG Wei,HUANG Xiaozhong,et al.Therapeutic evaluation of catheter-directed thrombolysis for the treatment of acute arterial ischemia of lower extremities[J].journal interventional radiology,2010,(08):715.

备注/Memo

备注/Memo:
收稿日期:2010-03-01
更新日期/Last Update: 2010-08-15