[1]张星,刘建民,黄清海.脑动脉瘤血流动力学数值模拟研究及其临床意义[J].介入放射学杂志,2008,(12):898-902.
　ZHANG Xing,LIU Jianming,HUANG Qinghai.Numerical virtual studies and clinical significance of the hemodynamics for cerebral aneurysms[J].journal interventional radiology,2008,(12):898-902.
点击复制

脑动脉瘤血流动力学数值模拟研究及其临床意义()

PDF下载中关闭

分享到：

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2008年12期
页码:
898-902
栏目:
综述
出版日期:
2008-12-15

文章信息/Info

Title:
Numerical virtual studies and clinical significance of the hemodynamics for cerebral aneurysms
作者:
张星; 刘建民; 黄清海
２００４３３上海第二军医大学长海医院神经外科
Author(s):
ZHANG Xing; LIU Jian－ming; HUANG Qing－hai．
Department of Neurosurgery，Changhai Hospital，Second Military Medical University，Shanghai２００４３３，China
关键词:
脑动脉瘤; 血流动力学; 数值模拟
分类号:
R７４３
文献标志码:
A
摘要:
血流动力学机制被认为是导致脑动脉瘤生长乃至破裂的主要因素。近年来数值模拟已成为脑动脉瘤血流动力学研究的重要方法，使目前对脑动脉瘤血流动力学机制的认识更为深入。本文回顾近年来的相关研究，对不同条件下动脉瘤内血流动力学包括速度场、壁面切应力、压力场等方面与脑动脉瘤生长、破裂等生物学行为之间的关系进行了总结，并对其临床意义进行了探讨。

参考文献/References:

［１］Burleson AC．Identification of quantifiable hemodynamic factors in the assessment of cerebral aneurysm behavior［J］．Thromb Haemost，１９９６，７６：１１８－１２３．
［２］Low M，Perktold K，Raunig R．Hemodynamics in rigid and distensible saccular aneurysms ：a numerical study of pulsatile flow characteristics［J］．Biorheology，１９９３，３０：２８７－２９８．
［３］Cangn G，Levy DI ，Lasheras JC．Flow changes caused by the sequential placement of stents across the neck of sidewall cerebral aneurysms ［J］．J Neurosurg，２００５，１０３：８９１－９０２．
［４］陈旭东，胡继良，杨新建，等．顶端动脉瘤的血流动力学数值模拟压力分析［J］．中国微侵袭神经外科杂志，２００４，９：２２２－２２４．
［５］Liepsch DW，Steiger HJ ，Poll A．Hemodynamic stress in lateral saccular aneurysms ［J］．Biorheology，１９８７，２４：６８９－７１０．
［６］Aenis M，Stancampiano A P，Wakhloo A K，et al．Modeling of flow in a straight stented and nonstented side wall aneurysm model［J］．J Biomech Eng，１９９７，１１９：２０６－２１２．
［７］Cebral JR，Castro MA，Burgess JE，et al．Characterization of cerebral aneurysms for assessing risk of rupture by using patient－specific computational hemodynamics models［J］．AJNR，２００５，２６：２５５０－２５５９．
［８］Metcalfe RW．The promise of computational fluid dynamics as a tool for delineating therapeutic options in the treatment of aneurysms ［J］．AJNR，２００３，２４：５５３－５５４．
［９］Liou TM，Chang TW，Chang WC．Pulsatile flow through a bifurcation with a cerebrovascular aneurysm［J］．J Biomech Eng，１９９４，１１６：１１２－１１８．
［１０］Burleson AC，Strother CM，Ttlritto VT．Computer modeling of intracranial saccular and lateral aneurysms for the study of their hemodynamics［J］．Neurosurgery，１９９５，３７：７７４－７８４．
［１１］Hoi Y，Meng H，Woodward SH，et al．Effects of arterial geo－metry on aneurysm growth：three－dimensional computational fluid dynamics study［J］．J Neurosurg，２００４，１０１：６７６－６８１．
［１２］Cebral JR，Castro MA，Appanaboyina S，et al．Efficient pipe－line for image－based patient－specific analysis of cerebral aneurysm hemodynamics：technique and sensitivity［J］．IEEE Trans Med Imaging，２００４，２４：４５７－４６７．
［１３］Vanninen R，Manninen H，Ronkainen A．Broad－based intrac－ranial aneurysms ：thrombosis induced by stent placement ［J］．AJNR，２００３，２４：２６３－２６６．
［１４］Ferguson GG．Physical factors in the initiation，growth，and rup－ture of human intracranial saccular aneurysms ［J］．J Neurosurg，１９７２，３７：６６６－６７７．
［１５］Krings T，Moller－Harmann W，Hans FJ．A refined method for creating saccular aneurysms in the rabbit［J］．Neuroradiology，２００３，４５：４２３－４２９．
［１６］Feng Y，Wada S，Tsubota K．The application of computer sim－ulation in the genesis and development of intracranial aneurysms ［J］．Technol Health Care，２００５，１３：２８１－２９１．
［１７］Cebral JR，Lhner R．From medical images to anatomically accurate finite element grids［J］．Int J Num Meth Eng，２００１，５１：９８５－１００８．
［１８］Ku DN．Blood flow in arteries［J］．Ann Rev Fluid Mechanics，１９９７，２９：３９９－４３４．
［１９］Lehoux S，Tronc F，Tedgui A．Mechanisms of blood flow－indu－ced vascular enlargement ［J］．Biorheology，２００２，３９：３１９－３２４．
［２０］Hashimoto T，Meng H，Young WL．Intracranial aneurysms ：links among inflammation，hemodynamics and vascular remodeling［J］．Neurol Res，２００６，２８：３７２－３８０．
［２１］Kondo S，Hashimoto S，Kikuchi H，et al．Cerebral aneurysms arising at nonbranching sites．An experimental study［J］．Stroke，１９９７，２８：３９８－４０４．
［２２］Suzuki J，Oharm H．Clinicopathological study of cerebral aneu－rysms ：origin，rupture and growth［J］．J Neurosurg，１９７８，４８：５０５－５２４．
［２３］Shojima M，Oshima M，Takagi K．Role of the bloodstream im－pacting force and the local pressure elevation in the rupture of cerebral aneurysms ［J］．Stroke，２００５，３６：１９３３－１９３８．
［２４］Krex D，Schackert HK，Schackert G．Genesis of cerebral aneurysms－an update［J］．Acta Neurochir（Wien），２００１，１４３：４２９－４４８．
［２５］Taddei S，Virdis A，Mattei P，et al．Vasodilation to acetyl－choline in primary and secondary forms of human hypertension［J］．Hypertension，１９９３，２１：９２９－９３３．
［２６］Savoia C，Schiffrin EL．Significance of recently identified pep－tides in hypertension：Endothelin，natriuretic peptides，adrenomedullin，leptin［J］．Med Clin North Am，２００４，８８：３９－６２．
［２７］Komatsu S，Panes J，Russell JM，et al．Effects of chronic ar－terial hypertension on constitutive and induced intercellular adhesion molecule－１expression in vivo［J］．Hypertension，１９９７，２９：６８３－６８９．
［２８］Nakatami H，Hashimoto N，Kang Y．Cerebral blood flow pat－terns at major vessel bifurcations and aneurysms in rats［J］．J Neurosurg，１９９１，７４：２５８－２６２．
［２９］Meng H，Feng Y，Woodward SH．Mathematical model of the rupture mechanism of intracranial saccular aneurysms through daughter aneurysm formation and growth［J］．Neurol Rese，２００５，２７：４５９－４６５．
［３０］Stuhne GR，Steinman DA．Finite－element modeling of the hemo－dynamics of stented aneurysms ［J］．J Biomechan Eng，２００４，１２６：３８２－３９０．
［３１］Ohta M，Wetzel SG，Dantan P．Rheological changes after sten－ting of a cerebral aneurysm：a finite element modeling approach［J］．Cardiovasc Intervent Radiol，２００５，２８：７６８－７７２．
［３２］Mitsos AD，Kakalis NMP ，Yiannis P，et al．Haemodynamic simulation of aneurysm coiling in an anatomically accurate computational fluid dynamics modeltechnical note［J］．Neuro－ra diology，２００７．

相似文献/References:

[1]尹化斌,季德林,宋树良,等.彩色多普勒在部分性脾栓塞范围控制中的临床应用[J].介入放射学杂志,2005,(06):641.
　YIN Hua-bin JI De-lin SONG Su-liang ZHU Jian-zhong YANG Yu-feng L(U) Shou-jin.The clinical study of the QC for PSE using color doppler[J].journal interventional radiology,2005,(12):641.
[2]何旭英,段传志,李铁林,等.脑动脉瘤血管内栓塞术中破裂的治疗[J].介入放射学杂志,2007,(02):132.
　HE Xu-ying,DUAN Chuan-zhi,LI Tie-lin,et al.Treatment of aneurysms rupture during endovascular embolization[J].journal interventional radiology,2007,(12):132.
[3]吴瑕,徐克,肖亮,等.血管内支架构型变化对血流动力学及支架内再狭窄形成的影响[J].介入放射学杂志,2009,(04):297.
　WU Xia,XU Ke,XIAO Liang,et al.The effect of stent structure changes on the hemodynamics and the formation of in－stent restenosis[J].journal interventional radiology,2009,(12):297.
[4]范一木,孙立军,王宏昭,等.三维影像在颅内动脉瘤栓塞中的应用[J].介入放射学杂志,2007,(08):513.
　FAN Yi-mu,SUN Li-jun,WANG Hong-zhao,et al.Three dimentional imagings in the application of intracranial aneurysm embolization[J].journal interventional radiology,2007,(12):513.
[5]曹俊杰,姚志超,刘占鳌,等.个体化经颈静脉肝内门体分流术血流动力学模拟研究[J].介入放射学杂志,2023,32(01):17.
　CAO Junjie,YAO Zhichao,LIU Zhanao,et al.Hemodynamic simulation study on individualized transjugular intrahepatic portosystemic shunt[J].journal interventional radiology,2023,32(12):17.
[6]张星,黄清海,施洋,等.支架孔率对脑动脉瘤血流动力学影响的三维数值模拟研究[J].介入放射学杂志,2009,(03):213.
　ZHANG Xing,HUANG Qinghai,SHI Yang,et al.Influence of stent porosity on cerebral intra－aneurysmal hemodynamics：a three－dimensional numerical simulative study[J].journal interventional radiology,2009,(12):213.

备注/Memo

备注/Memo:
收稿日期：２００８－０３－２６
更新日期/Last Update: 2008-12-15