[1]王海波,李 刚,陈清亮,等.早期剖宫产瘢痕妊娠子宫动脉栓塞后清宫术中大出血发生及其影响因素[J].介入放射学杂志,2023,32(05):436-440.
 WANG Haibo,LI Gang,CHEN Qingliang,et al.Massive haemorrhage during curettage after uterine artery embolization in early cesarean scar pregnancy and its influencing factors[J].journal interventional radiology,2023,32(05):436-440.
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早期剖宫产瘢痕妊娠子宫动脉栓塞后清宫术中大出血发生及其影响因素()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
32
期数:
2023年05
页码:
436-440
栏目:
血管介入
出版日期:
2023-05-30

文章信息/Info

Title:
Massive haemorrhage during curettage after uterine artery embolization in early cesarean scar pregnancy and its influencing factors
作者:
王海波 李 刚 陈清亮 梁 昊 杨 林 张 伟
Author(s):
WANG Haibo LI Gang CHEN Qingliang LIANG Hao YANG Lin ZHANG Wei.
Department of Radiology, Zhengzhou Municipal Seventh People’s Hospital, Zhengzhou, Henan Province 450016, China
关键词:
【关键词】 剖宫产瘢痕妊娠 子宫动脉 栓塞术 出血 危险因素
文献标志码:
A
摘要:
【摘要】 目的 探讨早期剖宫产瘢痕妊娠(CSP)患者子宫动脉栓塞术(UAE)后清宫术中大出血发生及其影响因素。方法 收集2015年1月1日至2021年12月31日3所医院出院的CSP患者临床资料,筛选出183例早期CSP患者。根据UAE后清宫术中是否发生子宫大出血,将患者分为大出血组(n=17)和非大出血组(n=166)。比较两组患者一般资料以及妊娠囊最大径、妊娠囊与膀胱后壁间子宫肌层厚度、妊娠囊血管化程度、妊娠囊侧支供血、妊娠囊供血血管未完全栓塞等指标。对组间比较差异有统计学意义的指标进行多因素logistic回归分析,绘制独立危险因素预测UAE后清宫术中大出血的受试者工作特征曲线(ROC),计算曲线下面积(AUC),比较AUC质量。结果 UAE后清宫术中大出血发生率为9.3%(17/183),未发生子宫切除及死亡等不良事件。两组年龄、孕期、末次剖宫产时间、妊娠囊最大径、妊娠囊血管化程度、妊娠囊侧支供血、妊娠囊供血血管未完全栓塞比较差异有统计学意义(均P<0.05)。多因素logistic回归分析结果显示,妊娠囊最大径(OR=1.064,95%CI=1.021~1.108,P=0.003)、妊娠囊侧支供血(OR=6.026,95%CI=0.030~0.918,P=0.040)、妊娠囊供血血管未完全栓塞(OR=0.071, 95%CI=0.005~33.330,P=0.045))是UAE后清宫术中大出血的独立危险因素。妊娠囊最大径、妊娠囊侧支供血、妊娠囊供血血管未完全栓塞预测UAE后清宫术中大出血的AUC分别为0.686(95%CI=0.541~0.831,P<0.05)、0.811(95%CI=0.680~0.942,P<0.01))、0.609(95%CI=0.449~0.768,P>0.05)。妊娠囊最大径与妊娠囊侧支供血、妊娠囊最大径与妊娠囊供血血管未完全栓塞间AUC质量相近(P>0.05),妊娠囊侧支供血的AUC质量优于妊娠囊供血血管未完全栓塞(P=0.002)。结论 早期CSP患者UAE后清宫术中仍可能发生大出血,对患者安全造成不利影响。妊娠囊最大径、妊娠囊侧支供血和妊娠囊供血血管未完全栓塞均有一定的提示UAE后清宫术中大出血的价值,相关研究仍有待深入。

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备注/Memo

备注/Memo:
(收稿日期:2022- 04-14)
(本文编辑:边 佶)
更新日期/Last Update: 2023-05-30