[1]张 源,沈加林,丁 敏,等.超声引导下125I粒子植入治疗胃癌肝转移38例[J].介入放射学杂志,2018,27(08):770-774.
 ZHANG Yuan,SHEN Jialin,DING Min,et al.Ultrasound- guided 125I seed brachytherapy for the treatment of gastric cancer with liver metastasis[J].journal interventional radiology,2018,27(08):770-774.
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超声引导下125I粒子植入治疗胃癌肝转移38例()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
27
期数:
2018年08期
页码:
770-774
栏目:
临床研究
出版日期:
2018-08-25

文章信息/Info

Title:
Ultrasound- guided 125I seed brachytherapy for the treatment of gastric cancer with liver metastasis
作者:
张 源 沈加林 丁 敏 杜冬伟 王振宇 李伟建 景宏舒 翟 博
Author(s):
ZHANG Yuan SHEN Jialin DING Min DU Dongwei WANG Zhenyu LI Weijian JING Hongshu ZHAI Bo.
Department of Interventional Oncology, Affiliated Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
关键词:
【关键词】 胃癌肝转移 放射治疗 125I粒子 临床疗效
文献标志码:
A
摘要:
【摘要】 目的 评价超声引导下125I粒子治疗胃癌肝转移的临床疗效。方法 38例胃癌肝转移患者术前利用计算机治疗计划系统(TPS)计算布源,术中行超声引导下125I粒子植入手术,术后进行剂量验证和质量评估。评价指标包括患者术后1、6个月肿瘤的CT、MR影像变化,术后并发症,肿瘤局部控制率和复发转移率,无进展生存期(PFS)和总生存期(OS)。结果 所有手术顺利完成,中位随访时间13个月。术后出现2例轻微疼痛,1例高胆红素血症,未见肝肾功能衰竭、放射性肠炎等严重并发症,无围手术期死亡。术后6个月肿瘤局部控制率80%,复发转移率28.9%;无瘤生存期5个月,6个月无瘤生存率46.9%;整体生存期16.4个月,6个月整体生存率81.4%。结论 超声引导下125I粒子植入治疗胃癌肝转移,临床近期疗效确切,是一种安全有效的治疗方法。

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备注/Memo

备注/Memo:
(收稿日期:2017-08-31)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2018-08-17