[1]吴 猛,周如海,袁 瑞,等.探讨超声引导下粗针穿刺组织学诊断乳腺浸润性小叶癌腋窝淋巴结转移的诊断价值 [J].介入放射学杂志,2018,27(04):340-344.
 WU Meng,ZHOU Ruhai,YUAN Rui,et al.Diagnostic value of ultrasound- guided core needle biopsy for axillary lymph node metastasis from invasive lobular carcinoma of the breast[J].journal interventional radiology,2018,27(04):340-344.
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探讨超声引导下粗针穿刺组织学诊断乳腺浸润性小叶癌腋窝淋巴结转移的诊断价值 
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
27
期数:
2018年04期
页码:
340-344
栏目:
非血管介入
出版日期:
2018-04-25

文章信息/Info

Title:
Diagnostic value of ultrasound- guided core needle biopsy for axillary lymph node metastasis from invasive lobular carcinoma of the breast
作者:
吴 猛 周如海 袁 瑞 赵 平 方来福
Author(s):
WU Meng ZHOU Ruhai YUAN Rui ZHAO Ping FANG Laifu
Department of Medical Ultrasound, Yinzhou People’s Hospital, Ningbo City, Zhejiang Province 315040, China
关键词:
【关键词】 乳腺癌 小叶癌 粗针穿刺 淋巴结转移
文献标志码:
A
摘要:
【摘要】 目的 探讨超声引导下粗针穿刺组织学诊断乳腺癌腋窝淋巴结转移的价值。方法 回顾性分析乳腺浸润性小叶癌患者的临床资料,比较高分辨率超声、超声引导下细针穿刺(US- FNAC)以及超声引导下粗针穿刺(US- CNB)诊断淋巴结转移的灵敏度、特异度和约登指数,术后病理检查结果作为金标准;免疫组织化学检测粗针穿刺物中雌激素(ER)、孕激素(PR)和人表皮生长因子受体2(HER2)3种蛋白的表达情况,并与术后病理免疫组化结果进行比较。结果 共纳入乳腺癌患者71例,腋窝超声探查80处可疑淋巴结;US- CNB组织活检诊断可疑淋巴结的灵敏度、特异度以及约登指数分别为85.07%,92.31%,77.38%;与US- FNAC诊断相比,US- CNB的灵敏度、特异度和约登指数更高,灵敏度差异有统计学意义(P<0.05);与US- FNAC检测相比,US- CNB的灵敏度、特异度和约登指数均有所提升;US- CNB免疫组织化学诊断ER、PR和HER2蛋白表达的灵敏度分别为97.22%,93.33%,93.33%,与术后肿瘤组织免疫组化结果相比,诊断的阳性率差异无统计学意义(P>0.05)。结论 US- CNB有助提升临床诊断乳腺浸润性小叶癌腋窝淋巴结的效率,粗针穿刺物免疫组织化学检测结果为临床辅助诊断乳腺癌患者基因表达情况提供一个新的方向。

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备注/Memo

备注/Memo:
(收稿日期:2017-05-15)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2018-04-16