[1]牛丹丹,万娅敏,周志刚,等.CT灌注联合能谱成像评价射频消融治疗肺癌近期疗效[J].介入放射学杂志,2016,(04):325-328.
 NIU Dan- dan,WAN Ya- min,ZHOU Zhi- gang,et al.Application of CT perfusion scanning combined with spectral imaging in evaluating the short- term effect of radiofrequency ablation for pulmonary adenocarcinomas[J].journal interventional radiology,2016,(04):325-328.
点击复制

CT灌注联合能谱成像评价射频消融治疗肺癌近期疗效 ()

PDF下载中关闭

分享到:

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2016年04期
页码:
325-328
栏目:
非血管介入
出版日期:
2016-04-25

文章信息/Info

Title:
Application of CT perfusion scanning combined with spectral imaging in evaluating the short- term effect of radiofrequency ablation for pulmonary adenocarcinomas
作者:
牛丹丹 万娅敏 周志刚 高剑波 潘元威 王 猛 杜可朴 李 帅 蒲 实
Author(s):
NIU Dan- dan WAN Ya- min ZHOU Zhi- gang GAO Jian- bo PAN Yuan- wei WANG Meng DU Ke- pu LI Shuai PU Shi
Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province 450052, China
关键词:
【关键词】 肺癌 射频消融 CT灌注 能谱成像
文献标志码:
A
摘要:
【摘要】 目的 探讨动态容积CT灌注联合能谱成像在射频消融(RFA)治疗肺癌近期疗效观察中的应用价值。方法 收集已经病理结果证实并拟行治疗的肺腺癌患者30例,术前1~2 d和术后30~40 d均行病灶部位灌注扫描,根据原始图像重建出能谱图像,并对比术前、术后灌注参数血流量(BF)、血容量(BV)、平均通过时间(MTT)、表面通透性(PS)及能谱参数碘(水)基值、水(碘)基值的变化,分析灌注参数及能谱参数对评价RFA治疗肺癌近期疗效的意义。结果 RFA后,全组患者的CT灌注参数及能谱参数值均值均下降,BF(t=7.34,P<0.001)、BV(t=4.721,P<0.001)、PS(t=2.224,P=0.034)、动脉期碘(水)基值(t=8.622,P<0.001)、静脉期碘(水)基值(t=6.608,P<0.001)及动脉期水(碘)基值(t=4.627,P<0.001)术前、术后近期差异有统计学意义。RFA前后,缓解组的各参数变化差值均大于复发组,但只有BF(Z=-2.806,P=0.005)、动脉期碘(水)基值(Z=-2.806,P=0.005)及静脉期碘(水)基值(Z=-4.208,P=0.014)变化差值有统计学意义。结论 CT灌注联合能谱成像是一种评价RFA治疗肺癌近期疗效的有效方法。

参考文献/References:

[1] Schneider T, Heussel CP, Herth FJ, et al. Thermal ablation of malignant lung tumors[J]. Dtsch Arztebl Int, 2013, 110: 394- 400.
[2] Siegel R, Ma J, Zou Z, et al. Cancer statistics, 2014[J]. CA Cancer J Clin, 2014, 64: 9- 29.
[3] Lencioni R, Crocetti L, Cioni R, et al. Radiofrequency ablation of lung malignancies: where do we stand?[J]. Cardiovasc Intervent Radiol, 2004, 27: 581- 590.
[4] 罗 君, 邵国良, 郑家平, 等. CT引导下射频消融治疗33例肺癌的回顾性分析[J]. 介入放射学杂志, 2015, 24: 530- 533.
[5] 张红丹, 崔燕海, 赵振军. 22例肺癌射频消融术后的CT随访观察[J]. 暨南大学学报?自然科学与医学版, 2013, 34: 231- 234.
[6] 谢海涛, 黎 庶, 初金刚, 等. CT灌注参数变化对肺癌化疗早期疗效的观察与评估[J]. 中国临床医学影像杂志, 2012, 23: 699- 702.
[7] 刘卫金, 张 冬, 杨春艳, 等. 肺部孤立性结节或肿块MSCT灌注成像与微血管密度的相关性研究[J]. 第三军医大学学报, 2008, 30: 1845- 1848.
[8] Lee TY, Purdie TG, Stewart E. CT imaging of angiogenesis[J]. Q J Nucl Med, 2003, 47: 171- 187.
[9] 任庆国, 滑炎卿, 李剑颖. CT能谱成像的基本原理及临床应用[J]. 国际医学放射学杂志, 2011, 34: 559- 563.
[10] 张家宙, 黄桂雄, 龙荣贵, 等. 宝石能谱CT的特点和临床应用[J]. 中国医学装备, 2013, 10: 57- 60.
[11] 王明亮, 缪 飞, 林晓珠, 等. CT能谱成像评价胰腺癌抗血管生成治疗效果的价值[J]. 放射学实践, 2012, 27: 246- 249.

相似文献/References:

[1]蒲红.上海市第二届射频消融疑难病例研讨会纪要[J].介入放射学杂志,1997,(01):63.
[2]蒲红,尹炯,王咏梅,等.显性间隔房室旁路的射频消融[J].介入放射学杂志,1997,(02):104.
[3]罗荣光,黄金华.肿瘤射频消融:电极的类型和消融灶的特点[J].介入放射学杂志,2011,(02):159.
 LUO Rong-guang,HUANG Jin-hua..Radiofrequency ablation of tumors: the relationship between the electrode type and the feature of ablated zone[J].journal interventional radiology,2011,(04):159.
[4]程洪涛,郭晨阳,黎海亮,等.TACE联合射频消融治疗原发性肝癌疗效的影响因素分析[J].介入放射学杂志,2012,(03):216.
 ,,et al.TACE combined with CTguided percutaneous radiofrequency ablation for the treatment of primary hepatocellular carcinomas: an analysis of factors affecting the therapeutic result [J].journal interventional radiology,2012,(04):216.
[5]姚红响,陈根生,诸葛英,等.肝动脉化疗栓塞联合CT引导射频消融序贯治疗中小肝癌的临床应用[J].介入放射学杂志,2012,(04):301.
 ,,et al.Sequential treatment with TACE and CTguided RFA for small and moderate sized HCC [J].journal interventional radiology,2012,(04):301.
[6]帕哈尔丁·白克热,杨树法,黄伍奎,等.肝动脉化疗栓塞联合射频消融术治疗30例原发性大肝癌的疗效评价[J].介入放射学杂志,2012,(04):322.
 ,,et al.TACE combined with radiofrequency ablation for massive primary hepatocellular carcinomas: a clinical therapeutic evaluation [J].journal interventional radiology,2012,(04):322.
[7]朱先海,吕维富,鲁 东,等.超选择性肾动脉栓塞术联合射频消融治疗肾癌的临床应用[J].介入放射学杂志,2011,(07):541.
 ZHU Xian-hai,LV Wei-fu,LU Dong,et al.Superselective renal artery embolization combined with radiofrequency ablation for the treatment of renal carcinomas: evaluation of clinical results[J].journal interventional radiology,2011,(04):541.
[8]谢小西,吕银祥,章宏欣,等. 肝动脉化疗栓塞、射频消融联合125Ⅰ粒子植入 治疗原发性肝癌的临床应用[J].介入放射学杂志,2011,(11):863.
 XIE Xiao-xi,LV Yin-xiang,ZHANG Hong-xin,et al.The clinical application of TACE together with RFA and 125Ⅰ seed implantation in treating hepatocellular carcinoma[J].journal interventional radiology,2011,(04):863.
[9]李建军,郑加生,崔雄伟,等. 肝肿瘤CT引导经皮射频消融术后胆道并发症防治[J].介入放射学杂志,2011,(12):984.
 LI Jian-jun,ZHENG Jia-sheng,CUI Xiong-wei,et al.The prevention and treatment of biliary complications occurred after CT-guided percutaneous radiofrequency ablation for hepatic neoplasms[J].journal interventional radiology,2011,(04):984.
[10]贺克武,高 斌,秦汉林,等. 125I粒子组织间植入联合支气管动脉灌注化疗治疗肺癌的疗效观察[J].介入放射学杂志,2012,(07):554.
 HE Ke- wu,GAO Bin,QIN Han- lin,et al.CT?蛳 guided percutaneous 125I seed implantation combined with bronchial arterial infusion chemotherapy for lung cancers: observation of therapeutic efficacy[J].journal interventional radiology,2012,(04):554.
[11]罗 君,邵国良,郑家平,等.CT引导下射频消融治疗33例肺癌的回顾性分析[J].介入放射学杂志,2015,(06):530.
 LUO Jun,SHAO Guo-liang,ZHENG Jia-ping,et al.CT-guided radiofrequency ablation for lung cancer: a retrospective analysis of 35 cases[J].journal interventional radiology,2015,(04):530.

备注/Memo

备注/Memo:
(收稿日期:2015-08-11)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2016-04-21