[1]朱国庆,虞希祥,肖池金,等. Embosphere微球联合碘油肝动脉栓塞治疗原发性肝癌破裂大出血25例疗效分析[J].介入放射学杂志,2014,(02):156-158.
 ZHU Guo? qing,YU Xi? xiang,XIAO Chi? jin,et al. Hepatic artery embolization with Embosphere microspheres and Lipiodol for the treatment of massive bleeding due to ruptured primary liver cancer: clinical results in 25 cases[J].journal interventional radiology,2014,(02):156-158.
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 Embosphere微球联合碘油肝动脉栓塞治疗原发性肝癌破裂大出血25例疗效分析 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年02期
页码:
156-158
栏目:
临床研究
出版日期:
2014-02-28

文章信息/Info

Title:
 Hepatic artery embolization with Embosphere microspheres and Lipiodol for the treatment of massive bleeding due to ruptured primary liver cancer: clinical results in 25 cases
作者:
 朱国庆 虞希祥 肖池金 乔彬彬 施振静 施昌盛 郑冰汝
Author(s):
 ZHU Guo?蛳 qing YU Xi?蛳 xiang XIAO Chi?蛳 jin QIAO Bin?蛳 bin SHI Zhen?蛳 jing SHI Chang?蛳 sheng ZHENG Bing?蛳 ru.
 Department of Interventional Radology, the Third Affiliated Hospital of Wenzhou Medical College, Ruian, Zhejiang Province 325200, China
关键词:
【关键词】 肝癌 出血 动脉栓塞 微球 
文献标志码:
A
摘要:
 【摘要】 目的 探讨Embosphere微球联合碘油肝动脉栓塞治疗原发性肝癌破裂大出血的疗效。 方法 对25例肝癌破裂大出血,急症行Embosphere微球联合碘油肝动脉栓塞治疗,分析其疗效。结果 肝癌破裂大出血25例,均为活动性大出血,Embosphere微球联合碘油介入手术栓塞止血成功24例,有效率为96%。术后平均动脉压由术前的(63.5 ± 16.8)mmHg上升至(83.5 ± 18.2)mmHg,与术前比较差异有统计学意义。术前ALT(141.3 ± 77.8)u/L,术后5 d(170.1 ± 98.6)u/L, 术前总胆红素(21.3 ± 7.1)μmol/L,术后5 d总胆红素(24.0 ± 9.1)μmol/L,肝功能术前术后无差别。术后1、3、6、12个月生存率分别为92%(23/25)、84%(21/25)、72%(18/25)、48%(12/25)。结论 Embosphere微球联合碘油肝动脉栓塞治疗原发性肝癌破裂大出血止血效果显著,创伤小,为后续治疗创造条件。

参考文献/References:

[1] Miyoshi A, Kitahara K, Kohya N, et al. Outcomes of patients with spontaneous rupture of hepatocellular carcinoma[J]. Hepatogastroenterology, 2011, 58: 99 ?蛳 102.
[2] Buczkowski AK, Kim PT, Ho SG, et al. Multidisciplinary management of ruptured hepatocellular carcinoma[J]. J Gastrointest Surg, 2006, 10: 379 ?蛳 386.
[3] Liu CL, Fan ST, Lo CM, et al. Management of spontaneous rupture of hepatocellular carcinoma: single?蛳 center experience[J]. J Clin Oncol, 2001, 19: 3725 ?蛳 3732.
[4] Li WH, Cheuk EC, Kowk PC, et al. Survival after transarterial embolization for spontaneous ruptured hepatocellular carcinoma[J]. J Hepatobiliary Pancreat Surg, 2009, 16: 508 ?蛳 512.
[5] Bruls S, Joskin J, Chauveau R, et al. Ruptured hepatocellular carcinoma following transcatheter arterial chemoembolization[J]. JBR?蛳 BTR, 2011, 94: 68 ?蛳 70.
[6] Kung CT, Liu BM, Ng SH, et al. Transcatheter arterial embolization in the emergency department for hemodynamic instability due to ruptured hepatocellular carcinoma: analysis of 167 cases[J]. Am J Roentgenol, 2008, 191: 231 ?蛳 239.
[7] 郑家生. 自发性肝癌破裂出血的急诊动脉栓寨治疗[J]. 介入放射学杂志, 2009, 18: 228 ?蛳 229.
[8] 赵广生, 徐 克, 梁松年, 等. 原发性肝癌TACE术后严重并发症原因及预防[J]. 介入放射学杂志, 2008, 17: 773 ?蛳 775.
[9] Yamamoto A, Imai S, Kobatake M, et al. Evaluation of tris?蛳 acryl gelatin microsphere embolization with monochromatic X Rays: comparison with polyvinyl alcohol particles[J]. J Vasc Interv Radiol, 2006, 17: 1797 ?蛳 1802.
[10] Ohta S, Nitta N, Takahashi M, et al. Degradable gelatin microspheres as an embolic agent: an experimental study in a rabbit renal model[J]. Korean J Radiol, 8: 418 ?蛳 428. 

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备注/Memo

备注/Memo:
 (收稿日期:2013-06-18)
更新日期/Last Update: