[1]王卫国,谢其根,吴春根,等.射频消融联合椎体成形术治疗脊柱转移瘤105例[J].介入放射学杂志,2012,(09):747-751.
 WANG Wei- guo,XIE Qi- gen,WU Chun- gen,et al. Radiofrequency ablation combined with percutaneous vertebroplasty therapy for spinal metastases: an initial experience in 105 cases[J].journal interventional radiology,2012,(09):747-751.
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射频消融联合椎体成形术治疗脊柱转移瘤105例 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2012年09期
页码:
747-751
栏目:
非血管介入
出版日期:
2012-09-30

文章信息/Info

Title:
 Radiofrequency ablation combined with percutaneous vertebroplasty therapy for spinal metastases: an initial experience in 105 cases
作者:
 王卫国 谢其根 吴春根 顾一峰 程永德
Author(s):
 WANG Wei- guo XIE Qi- gen WU Chun- gen GU Yi- feng CHENG Yong- de.
 Department of Interventional Radiology, Wuxi Municipal Fourth People’s Hospital, Wuxi Jiangsu Province 214062, China
关键词:
 【关键词】 脊柱转移瘤 射频消融术 经皮椎体成形术 骨水泥外漏
文献标志码:
A
摘要:
 【摘要】 目的 探讨射频消融(RFA)联合经皮椎体成形术(PVP)治疗脊柱转移瘤的临床疗效与安全性。方法 分析2009年6月至2011年6月于无锡市第四人民医院及上海市第六人民医院行RFA联合PVP或单纯PVP治疗脊柱转移瘤362例,选择其中具有完整资料的226例为研究对象,其中RFA联合PVP组(A组)105例,153节椎体;单纯PVP组(B组)121例,190节椎体。比较患者疼痛缓解情况,采用配对t检验对所得数据进行统计学分析。比较两组骨水泥的外漏率、外漏类型,采用R × C列联表χ2检验进行统计学分析。结果 疼痛缓解根据WHO标准,A组术后1 d、1周、1个月、3个月的有效率为分别为83.8%、86.9%、87.2%和82.2%;B组同期有效率分别为81.0%、83.6%、84.1%和80.5%,经配对t检验,术后随访时间段两组患者疼痛均得到明显缓解(P < 0.05),两组间疗效差异无统计学意义(P > 0.05)。A组和B组骨水泥外漏发生率分别为17.6%和37.4%,采用C列联表χ2检验,差异有统计学意义(P < 0.05);A组未出现神经根压迫症状,B组有3例患者出现神经根压迫症状,用激素、脱水、止痛对症治疗后好转。结论 RFA联合PVP与单纯PVP治疗脊柱转移瘤均具有良好的止痛效果,两组术后疗效对比分析差异无统计学意义;A组骨水泥外漏少于B组,PVP之前行RFA可减少骨水泥外渗。

参考文献/References:

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备注/Memo

备注/Memo:
 (收稿日期:2012-03-21)
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