[1]岑锦明,熊卿圆,杨希立,等. 糖化血红蛋白与冠状动脉支架术后再狭窄的关系[J].介入放射学杂志,2012,(09):725-727.
 CEN Jin- ming,XIONG Qing- yuan,YANG Xi- li,et al. Relationship between glycated hemoglobin and restenosis after percutaneous coronary intervention procedure[J].journal interventional radiology,2012,(09):725-727.
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 糖化血红蛋白与冠状动脉支架术后再狭窄的关系 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2012年09期
页码:
725-727
栏目:
心脏介入
出版日期:
2012-09-30

文章信息/Info

Title:
 Relationship between glycated hemoglobin and restenosis after percutaneous coronary intervention procedure
作者:
 岑锦明 熊卿圆 杨希立 柯媛媛 许兆延
Author(s):
 CEN Jin- ming XIONG Qing- yuan YANG Xi- li KE Yuan- yuan XU Zhao- yan.
  Department of Cardiology, Foshan Municipal First People’s Hospital, Foshan, Guangdong Province 528000, China
关键词:
 【关键词】 糖化血红蛋白 支架内再狭窄 血管内超声
文献标志码:
A
摘要:
 【摘要】 目的 应用血管内超声(IVUS)研究糖化血红蛋白(HbA1c)与冠状动脉(冠脉)支架植入术后再狭窄的关系。方法 将178例成功接受支架植入术的冠心病患者,根据HbA1c水平分为三组,HbA1c < 6.0%组、HbA1c 6.0% ~ 7.0%组、HbA1c > 7.0%组。用冠脉造影(CAG)及IVUS随访6 ~ 12个月,以CAG直径狭窄率 ≥ 50%为支架内再狭窄,用IVUS观察三组冠脉支架术后最小管腔面积、斑块负荷、新生内膜面积,初步探讨HbA1c与再狭窄的关系。结果 178例患者共201处病变,CAG随访示支架内再狭窄30例,再狭窄率14.9%,再狭窄患者的HbA1c水平为6.87% ± 0.56 %,明显高于无再狭窄患者的6.05% ± 0.47%,两组间差异有统计学意义(P = 0.017),其中HbA1c < 6.0%组发生再狭窄10例,HbA1c 6.0% ~ 7.0%组8例,HbA1c > 7.0%组12例,HbA1c > 7.0%组再狭窄率为31.6%,明显高于HbA1c 6.0% ~ 7.0%组的13.8% 和HbA1c ≤ 6.0%组的9.5%(P < 0.01)。相关分析表明HbA1c与新生斑块面积和斑块负荷呈正相关(r分别为0.685和0.617,P < 0.01)。结论 HbA1c升高可能与冠脉内膜增生有关,测定HbA1c有助于评估冠脉支架术后再狭窄的风险,控制好HbA1c对预防冠脉支架植入后再狭窄有一定价值。 

参考文献/References:

 [1] Zhu W, Sun T, Shi H, et al. Combined effects of glycated hemoglobin A1c and blood pressure on carotid artery atherosclerosis in nondiabetic patients[J]. Clin Cardiol, 2010, 33: 542 ?蛳 547.
[2] Rivera JJ, Choi EK, Yoon YE, et al. Association between increasing levels of hemoglobin A1c and coronary atherosclerosis in asymptomatic individuals without diabetes mellitus[J]. Coron Artery Dis, 2010, 21: 157 ?蛳 163.
[3] Ueda H, Mitsusada N, Harimoto K, et al. Glycosylated hemoglobin is a predictor of major adverse cardiac events after drug?蛳eluting stent implantation in patients with diabetes mellitus[J]. Cardiology, 2010, 116: 51 ?蛳 57.
[4] Diedrichs H, Pfister R, Hagemeister J, et al. An increase in HbA1c after percutaneous coronary intervention raises the risk for restenosis in patients without type 2 diabetes mellitus[J]. Diabet Med, 2008, 25: 228 ?蛳 231.
[5] Sahara M, Kirigaya H, Oikawa Y, et al. Soft plaque detected on Intravascular ultrasound is the strongest predictor of in?蛳stent restenosis: an intravascular ultrasound study[J]. Eur Heart J, 2004, 25: 2026 ?蛳 2033.
[6] 田 磊, 米树华, 苏 工, 等. 非糖尿病人群糖化血红蛋白水平与冠心病发病的关系[J]. 中国糖尿病杂志, 2007, 15: 598 ?蛳 600.

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备注/Memo

备注/Memo:
 (收稿日期:2012-02-25)
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