[1]王福安,季杰,马园,等.微波或射频消融联合骨水泥成形术及单纯骨水泥成形术治疗椎体转移性肿瘤[J].介入放射学杂志,2025,34(03):268-271.
 WANG Fuan,JI Jie,MA Yuan,et al.Microwave ablation or radiofrequency ablation combined with bone cement augmentation and simple bone cement augmentation for vertebral metastatic tumors[J].journal interventional radiology,2025,34(03):268-271.
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微波或射频消融联合骨水泥成形术及单纯骨水泥成形术治疗椎体转移性肿瘤()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
34
期数:
2025年03
页码:
268-271
栏目:
非血管介入
出版日期:
2025-03-25

文章信息/Info

Title:
Microwave ablation or radiofrequency ablation combined with bone cement augmentation and simple bone cement augmentation for vertebral metastatic tumors
作者:
王福安季杰马园周文杰颜波吕朋华
Author(s):
WANG Fu′anJI JieMA YuanZHOU WenjieYAN BoLV Penghua.
Department of Interventional Radiology,Northern Jiangsu People′s Hospital,Yangzhou,Jiangsu Province 225002,China
关键词:
【关键词】脊柱转移癌疼痛微波消融射频消融椎体成形术
文献标志码:
A
摘要:
【摘要】目的探讨微波消融(MWA)联合经皮椎体成形术(PVP)与射频消融(RFA)联合PVP及单纯PVP治疗椎体转移性肿瘤的临床疗效。方法纳入2019年1月至2023年6月苏北人民医院接受MWA联合PVP(M+P组)、RFA联合PVP(R+P组)及单纯PVP(P组)治疗椎体转移肿瘤患者65例。其中M+P组25例(27节椎体),R+P组20例(23节椎体),P组20例(24节椎体)。采用视觉模拟评分法(VAS)评估患者的术前疼痛及术后缓解情况。评估术后1周骨水泥分布和渗漏情况。结果3组患者均顺利完成手术,均未发生操作相关的严重并发症。术前R+P组、P组、M+P组患者VAS评分分别为(8.48±0.80)分、(8.57±0.98)分、(8.20±1.00)分,差异无统计学意义(P>0.05)。术后1周3组患者疼痛均明显减轻,VAS评分分别为(4.10±0.85)分、(3.17±0.93)分、(2.44±1.23)分,M+P组VAS评分降低最明显(P<0.05)。术后6个月VAS评分分别为(1.87±0.84)分、(4.60±1.09)分、(1.48±0.71)分,M+P组VAS评分降低最明显(P<0.05)。M+P组患者的骨水泥注射量为(7.54±1.44) mL,R+P组为(5.48±1.12) mL,P组为(4.59±1.56) mL,差异有统计学意义(P<0.05)。P组的血管性渗漏率(34.8%)及非血管渗漏率(52.2%)显著高于R+P组及M+P组(P<0.05),R+P组与M+P组的骨水泥渗漏率差异均无统计学意义(P>0.05)。结论MWA联合PVP治疗椎体转移瘤的疼痛缓解率好于RFA联合PVP及单纯PVP。

参考文献/References:

[1]Morimoto T,Toda Y,Hakozaki M,et al.A new era in the management of spinal metastasis[J].Front Oncol,2024,14:1374915.
[2]Qiao RQ,Zhang HR,Ma RX,et al.Prognostic factors for bone survival and functional outcomes in patients with breast cancer spine metastases[J].Technol Cancer Res Treat,2022,21:15330338221122642.
[3]Barzilai O,Fisher CG,Bilsky MH.State of the art treatment of spinal metastatic disease[J].Neurosurgery,2018,82:757-769.
[4]Zhang HR,Xu MY,Yang XG,et al.Percutaneous vertebral augmentation procedures in the management of spinal metastases[J].Cancer Lett,2020,475:136-142.
[5]Wang Z,Zuo T,Lin W,et al.Safety and clinical efficacy of microwave ablation combined with percutaneous vertebroplasty in the treatment of multisegmental spinal metastases[J].J Cancer Res Ther,2024,20:712-717.
[6]Wu L,Hu M,Li P,et al.Microwave ablation combined with percutaneous vertebroplasty for treating painful non-small cell lung cancer with spinal metastases under real-time temperature monitoring[J].J Cancer Res Ther,2024,20:540-546.
[7]杨威,胡婷业,陆玉和,等.微波消融联合经皮椎体成形术治疗椎体转移性肿瘤的疗效观察[J].介入放射学杂志,2020,29:1146-1150.
[8]Hoskin PJ,Hopkins K,Misra V,et al.Effect of single-fraction vs multifraction radiotherapy on ambulatory status among patients with spinal canal compression from metastatic cancer:the SCORAD randomized clinical trial[J].JAMA,2019,322:2084-2094.
[9]Rades D,Veninga T,Stalpers LJ,et al.Outcome after radiotherapy alone for metastatic spinal cord compression in patients with oligometastases[J].J Clin Oncol,2007,25:50-56.
[10]Jawad MS,Fahim DK,Gerszten PC,et al.Vertebral compression fractures after stereotactic body radiation therapy:a large,multi-institutional,multinational evaluation[J].J Neurosurg Spine,2016,24:928-936.
[11]Patel B,DeGroot H.Evaluation of the risk of pathologic fractures secondary to metastatic bone disease[J].Orthopedics,2001,24:612-617.
[12]Xie L,Zhao ZG,Zhang SJ,et al.Percutaneous vertebroplasty versus conservative treatment for osteoporotic vertebral compression fractures:an updated meta-analysis of prospective randomized controlled trials[J].Int J Surg,2017,47:25-32.
[13]夏磊,王凯,陆玉和.经皮微波消融联合椎体成形术治疗脊柱转移性肿瘤[J].齐齐哈尔医学院学报,2020,41:688-690.
[14]胡继红,王会,赵卫,等.射频消融联合椎体成形术治疗脊柱转移性肿瘤12例[J].介入放射学杂志,2013,22:563-566.
[15]黄洪彬.微创经皮椎体成形术联合射频消融术治疗脊柱转移性肿瘤的疗效[J].中国实用医药,2022,17:25-28.
[16]Mayer T,Cazzato RL,De Marini P,et al.Spinal metastases treated with bipolar radiofrequency ablation with increased (>70 ℃) target temperature:Pain management and local tumor control[J].Diagn Interv Imaging,2021,102:27-34.
[17]Tomasian A,Jennings JW.Spine microwave ablation:safety and efficacy for treatment of vertebral metastases[J].AJNR Am J Neuroradiol,2022,43:E9-E10.
[18]Kassamali RH,Ganeshan A,Hoey ETD,et al.Pain management in spinal metastases:the role of percutaneous vertebral augmentation[J].Ann Oncol,2011,22:782-786.
[19]Cotten A,Dewatre F,Cortet B,et al.Percutaneous vertebroplasty for osteolytic metastases and myeloma:effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up[J].Radiology,1996,200:525-530.
[20]Reyad RM,Ghobrial HZ,Hakim SM,et al.Thick cement usage in percutaneous vertebroplasty for malignant vertebral fractures at high risk for cement leakage[J].Diagn Interv Imaging,2017,98:721-728.
[21]Georgy BA.Bone cement deposition patterns with plasma-mediated radio-frequency ablation and cement augmentation for advanced metastatic spine lesions[J].AJNR Am J Neuroradiol,2009,30:1197-1202.
[22]Schaefer O,Lohrmann C,Markmiller M,et al.Technical innovation.Combined treatment of a spinal metastasis with radiofrequency heat ablation and vertebroplasty[J].AJR Am J Roentgenol,2003,180:1075-1077.

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备注/Memo

备注/Memo:
(收稿日期:2024-08-05)
(本文编辑:新宇)
更新日期/Last Update: 2025-03-25