[1]王世知,赵文鹏,周为民.3%聚多卡醇联合无水乙醇硬化治疗肢体静脉畸形的效果[J].介入放射学杂志,2023,32(02):123-126.
　WANG Shizhi,ZHAO Wenpeng,ZHOU Weimin..The clinical effect of DSA-guided percutaneous sclerotherapy using 3% polidocanol combined with absolute ethanol in the treatment of venous malformation of limbs[J].journal interventional radiology,2023,32(02):123-126.
点击复制

3%聚多卡醇联合无水乙醇硬化治疗肢体静脉畸形的效果()

PDF下载中关闭

分享到：

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
32
期数:
2023年02
页码:
123-126
栏目:
血管介入
出版日期:
2023-03-03

文章信息/Info

Title:
The clinical effect of DSA-guided percutaneous sclerotherapy using 3% polidocanol combined with absolute ethanol in the treatment of venous malformation of limbs
作者:
王世知; 　赵文鹏; 　周为民
Author(s):
WANG Shizhi;  ZHAO Wenpeng;  ZHOU Weimin.
Department of Vascular Surgery, Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province 330006, China
关键词:
【关键词】 静脉畸形; 硬化疗法; 聚多卡醇; 无水乙醇
文献标志码:
A
摘要:
【摘要】　目的　探讨DSA导引下经皮注射3%聚多卡醇联合无水乙醇治疗肢体静脉畸形的临床效果。方法　收集2019年7月至2020年7月南昌大学第二附属医院收治的32例肢体静脉畸形患者临床资料。其中男12例，女20例，年龄10～52岁。根据术前MRI检查和术中血管造影，Puig分型Ⅰ型6例，Ⅱ型20例，Ⅲ型3例，Ⅳ型3例。所有患者均在局部麻醉下接受3%聚多卡醇联合无水乙醇硬化治疗。术后4周复查MRI，记录病灶大小并计算病灶缩小率。随访6～12个月。结果　32例中26例为低回流型静脉畸形，6例为高回流型静脉畸形。术后6例PuigⅠ型患者治愈，20例Ⅱ型患者基本治愈，6例Ⅲ、Ⅳ型患者均有效，治疗有效率为100%。出现局部张力性水泡2例，局部色素沉着3例，未出现皮肤坏死表现。 结论　3%聚多卡醇联合无水乙醇硬化治疗肢体静脉畸形安全有效，并发症较少。

参考文献/References:

［1］Richter GT， Friedｍan AB. Hemangiomasand vascular malformations: current theory and manaegment ［J］. Int J Pediatr, 2012, 2012：645678.
［2］ Hou F, Chen J, Xia M, et al. Percutaneous sclerotherapy with polidocanol under the guidance of ultrasound for venous malformations in children: a retrospective cohort study from a single tertiary medical center［J］. Medicine （Baltimore）, 2020, 99:e18839.
［3］　Bai N, Chen YZ, Fu YJ, et al. A clinical study of pingyangmycin sclerotherapy for venous malformation: an evaluation of 281 consecutive patients［J］. J Clin Pharm Ther, 2014, 39：521-526.
［4］　Yakes W, Yakes A, Rohlffs F, et al. Current controversies and the state of the art in endovascular treatment of vascular malformations［J］. J Interv Med, 2018, 1:65-69.
［5］ Puig S, Casati B, Staudenherz A, et al. Vascularlow-flow malformations in children: current concepts for classification, diagnosis and therapy［J］. Eur J Radiol, 2005, 53:35-45.
［6］　中华医学会整形外科分会血管瘤和脉管畸形学组. 血管瘤和脉管畸形诊断和治疗指南（2019版）［J］. 组织工程和重建外科杂志，2019，15:277-317
［7］　张　靖，李海波，周少毅，等. 儿童静脉畸形介入治疗硬化剂无水乙醇与平阳霉素效果的对比研究［J］. 中华放射学杂志， 2012， 46： 350-353.
［8］ Kim B, Kim K, Jeon P, et al. Long-term results of ethanol sclerotherapy with or without adjunctive surgery for head and neck arteriovenous malformations ［J］. Neuroradiology, 2015, 57：377-386.
［9］　国际血管联盟中国分部血管畸形专家委员会.静脉畸形中国专家共识［Ｊ］. 介入放射学杂志，2019，28：307-311.
［10］ Richter GT, Braswell L. Mansgement of venous malformations［J］.Facial Plast Surg, 2012, 28：603-610.
［11］ 牛传强，刘珍银，张　靖，等. 弹簧钢圈联合无水乙醇栓塞硬化治疗复杂型静脉畸形［J］. 中华放射学杂志，2016，50:963-967.
［12］ Steiner F, FitzJohn T, Tan ST. Ethanol sclerotherapy for venous malformation［J］. ANZ J Surg, 2016, 86:790-795.
［13］ Mitchell SE, Shah AM, Schwengel D. Pulmonary artery pressure changes during ethanol embolization procedures to treat vascular malformations: can cardiovascular collapse be predicted［J］. J Vasc Interv Radiol, 2006, 17（2 Pt 1）: 253-262.
［14］ Ko JS, Kim JA, Do YS, et al. Prediction of the effect of injected ethanol on pulmonary arterial pressure during sclerotherapy of arteriovenous malformations: relationship with dose of ethanol［J］. J Vasc Interv Radiol, 2009, 20: 39-45.
［15］ Shin BS, Do YS, Cho HS, et al. Cardiovascular effects and predictability of cardiovascular collapse after repeated intravenous bolus injections of absolute ethanol in anesthetized pigs［J］. J Vasc Interv Radiol, 2010, 21: 1867-1872.
［16］ Wang D, Su L, Fan X. Cardiovascular collapse and disseminated intravascular coagulation as complications of ethanol embolization of arteriovenous malformations in the upper lip: case report and literature review［J］. J Oral Maxillofac Surg, 2014, 72: 346- 351.
［17］ Rimon U, Garniek A, GaliliY, et al. Ethanol sclerotherapy of peripheral cenous malformations［J］Eur J Radiol, 2004, 52：283- 287.
［18］ 曾德筠，廖良忠，杨维竹. 硬化剂治疗头颈部静脉畸形临床疗 效及作用机制研究 ［J］. 介入放射学杂志，2016，25:1049-1053.

相似文献/References:

[1]张靖,徐宏文,周少毅,等.经导管动脉栓塞联合局部硬化治疗儿童四肢巨大血管瘤[J].介入放射学杂志,2010,(07):527.
　ZHANG Jing,XU Hongwen,ZHOU Shaoyi,et al.Transcatheter arterial embolization combined with local sclerotherapy for the treatment of giant hemangiomas of extremities in children[J].journal interventional radiology,2010,(02):527.
[2]李海波,张 靖,周少毅,等. DSA引导下泡沫硬化剂治疗儿童静脉畸形的临床观察[J].介入放射学杂志,2013,(09):738.
　LI Hai? bo,ZHANG Jing,ZHOU Shao? yi,et al. DSA?蛳 guided foam sclerotherapy for the treatment of venous malformations in children： clinical observation[J].journal interventional radiology,2013,(02):738.
[3]曾德筠,廖良忠,杨维竹.硬化剂治疗头颈部静脉畸形临床疗效及作用机制研究[J].介入放射学杂志,2016,(12):1049.
　ZENG De- jun,LIAO Liang- zhong,YANG Wei- zhu.The utilization of hardening agent for the treatment of cephalocervical venous malformations： study of its clinical efficacy and mechanism[J].journal interventional radiology,2016,(02):1049.
[4]国际血管联盟中国分部血管畸形专家委员会.静脉畸形中国专家共识 [J].介入放射学杂志,2019,28(04):307.
　Committee of Experts on Vascular Malformations,Chinese Chapter of International Union of Angiology..Consensus of Chinese experts on venous malformations[J].journal interventional radiology,2019,28(02):307.
[5]夏志鹏,袁 瑛,陶晓峰.静脉畸形硬化治疗效果影像学评价[J].介入放射学杂志,2020,29(11):1165.
　XIA Zhipeng,YUAN Ying,TAO Xiaofeng..Imaging evaluation of the curative effect of sclerotherapy for venous malformation[J].journal interventional radiology,2020,29(02):1165.
[6]王 蒙,陈晓峰,张 强,等.聚桂醇联合不同浓度平阳霉素介入治疗肢体低流速静脉畸形的疗效[J].介入放射学杂志,2024,33(05):483.
　WANG Meng,CHEN Xiaofeng,ZHANG Qiang,et al.Lauromacrogol combined with different concentrations of pingyangmycin for low-flow venous malformations of limbs： analysis of therapeutic effect[J].journal interventional radiology,2024,33(02):483.

备注/Memo

备注/Memo:
（收稿日期：2021-12-26）
（本文编辑：边　佶）
更新日期/Last Update: 2023-03-03