[1]李玉婷,赵敏竹,杨晋辉.球囊阻断逆行经静脉闭塞术治疗失代偿期肝硬化胃静脉曲张12例效果分析[J].介入放射学杂志,2023,32(02):168-172.
　LI Yuting,ZHAO Minzhu,YANG Jinhui..Balloon-occluded retrograde transvenous obliteration for gastric varices in patients with decompensated cirrhosis: analysis of curative effect in 12 patients[J].journal interventional radiology,2023,32(02):168-172.
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球囊阻断逆行经静脉闭塞术治疗失代偿期肝硬化胃静脉曲张12例效果分析()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
32
期数:
2023年02
页码:
168-172
栏目:
临床研究
出版日期:
2023-03-03

文章信息/Info

Title:
Balloon-occluded retrograde transvenous obliteration for gastric varices in patients with decompensated cirrhosis: analysis of curative effect in 12 patients
作者:
李玉婷; 　赵敏竹; 　杨晋辉
Author(s):
LI Yuting;  ZHAO Minzhu;  YANG Jinhui.
Department of Gastroenterology, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province 650101, China
关键词:
【关键词】 肝硬化; 门静脉高压; 胃静脉曲张; 球囊阻断逆行经静脉闭塞术
文献标志码:
A
摘要:
【摘要】 目的　评价球囊阻断逆行经静脉闭塞术（BRTO）治疗失代偿期肝硬化胃静脉曲张（GV）的临床效果。 方法　回顾性分析2019年8月至2021年3月在昆明医科大学第二附属医院接受BRTO治疗的12例肝硬化GV患者临床资料。观察治疗前后静脉曲张栓塞效果，术后再出血率、肝功能变化及手术相关并发症。 结果　12例患者BRTO手术均获成功。与手术前相比，术后患者总胆红素（TBil）明显降低［15.60（8.55，31.28） μmol/L比22.60（14.60,31.80） μmol/L，P=0.005］，凝血酶原时间（PT）缩短［（15.57±2.14） s比（16.45±2.19） s，P=0.034］；血清白蛋白（ALB）、丙氨酸转氨酶（ALT）、天冬氨酸转氨酶（AST）、谷氨酰转移酶（GGT）水平有所升高（均P＞0.05）；血清肌酐（Crea）、血小板（PLT）、凝血酶原时间（PT）、国际标准化比值（INR）水平有所下降（均P＞0.05）；Child-Pugh评分无明显变化，但终末期肝病模型（MELD）评分显著降低［（9.92±2.28）分比（10.92±2.91）分，P=0.002］。Kaplan-Meier分析显示，术后3、6、12个月累积再出血率分别为16.7%、25.9%、35.2%，术后12个月病死率为9.1%。结论　BRTO治疗GV可行、安全有效，可在止血的同时改善患者肝功能，但可能有食管静脉曲张和腹水加重风险，需进一步评估远期疗效。

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备注/Memo

备注/Memo:
（收稿日期：2021-12-30）
（本文编辑：边　佶）
更新日期/Last Update: 2023-03-03