[1]徐 圣,张学军,石宝琪,等.微波消融联合经导管动脉化疗栓塞术治疗肝细胞癌生存预测[J].介入放射学杂志,2020,29(05):508-513.
　XU Sheng,ZHANG Xuejun,SHI Baoqi,et al.The survival prediction for HCC patients receiving microwave ablation combined with TACE[J].journal interventional radiology,2020,29(05):508-513.
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微波消融联合经导管动脉化疗栓塞术治疗肝细胞癌生存预测()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
29
期数:
2020年05
页码:
508-513
栏目:
临床研究
出版日期:
2020-05-25

文章信息/Info

Title:
The survival prediction for HCC patients receiving microwave ablation combined with TACE
作者:
徐 圣;  张学军;  石宝琪;  谭永胜;  朝鲁孟
Author(s):
XU Sheng;  ZHANG Xuejun;  SHI Baoqi;  TAN Yongsheng;  CHAO Lumeng.
Department of Interventional Diagnosis and Treatment， People’s Hospital of Inner Mongolia Autonomous Region， Hohhot， Inner Mongolia Autonomous Region 010017， China
关键词:
【关键词】 肝细胞肝癌;  微波消融;  经导管动脉化疗栓塞术;  生存期;  预测
文献标志码:
A
摘要:
【摘要】 目的 探讨影响微波消融（MWA）联合TACE治疗肝细胞癌（HCC）患者总生存期（OS）的预测因素，并对患者OS进行有效预测。方法 回顾性分析2013年1月至2017年3月行MWA联合TACE治疗的HCC患者59例。以OS为基础，针对13项潜在因素，采用单因素分析（Log- rank检验）及Cox多因素回归分析探讨影响OS的预测因素，并采用R软件构建预后列线图（nomogram）以预测OS，使用Harrell’s c statistic评价其准确性。 结果 59例患者的中位OS（mOS） 为（24.0±11.6） 个月，中位肿瘤进展时间为（10.3±5.9）个月。单因素分析及Cox多因素回归分析显示门静脉癌栓（PVTT）、甲胎蛋白（AFP）≥400 ng/mL、最大肿瘤直径≥7 cm是影响OS的预测因素。预后计算图（nomogram）的准确度评价Harrell’s c statistic为0.81。 结论 PVTT、AFP≥400 ng/mL、最大肿瘤直径≥7 cm是影响MWA联合TACE治疗HCC患者OS的预测因素，预后计算图可准确预测患者的OS。

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备注/Memo

备注/Memo:
（收稿日期：2019- 05- 30）
（本文编辑：俞瑞纲）
更新日期/Last Update: 2020-05-22