[1]马建兵,杨朝爱,江 旭,等.TACE治疗胰腺神经内分泌肿瘤肝转移的疗效分析 [J].介入放射学杂志,2019,28(05):468-471.
 MA JianbingYANG Chaoai,JIANG Xu,LIU Hang,et al.TACE for the treatment of hepatic metastases from pancreatic neuroendocrine tumors: evaluation of its curative effect ,[J].journal interventional radiology,2019,28(05):468-471.
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TACE治疗胰腺神经内分泌肿瘤肝转移的疗效分析


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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
28
期数:
2019年05期
页码:
468-471
栏目:
临床研究
出版日期:
2019-05-25

文章信息/Info

Title:
TACE for the treatment of hepatic metastases from pancreatic neuroendocrine tumors: evaluation of its curative effect ,
作者:
马建兵 杨朝爱 江 旭 刘 航 罗 荣 吴林霖 杨继金 孙军辉
Author(s):
MA JianbingYANG Chaoai JIANG Xu LIU Hang LUO Rong WU Linlin YANG Jijin SUN Junhui.
Hepatobiliary and Pancreatic Intervention Center, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province 310003, China
关键词:
【关键词】 胰腺 神经内分泌肿瘤 肝转移 肝动脉化疗栓塞
文献标志码:
A
摘要:
【摘要】 目的 评估肝动脉化疗栓塞(TACE)治疗胰腺神经内分泌肿瘤(PNET)肝转移的疗效。方法回顾性收集经手术或穿刺病理证实的25例PNET肝转移行TACE治疗的患者资料,共进行了87次TACE术。经MRI评价其有效率,并分析无进展生存期(PFS)、总生存期(OS)和并发症。结果 所有25例患者均顺利完成介入治疗。MRI疗效评估结果为CR 0例,PR 15例,SD 4例,PD 6例,有效率60.0%;中位PFS 13个月,中位OS 18个月;1例术中出现假性动脉瘤,所有病例术后均无严重并发症。结论 对于不能手术切除的PNET肝转移患者,行TACE治疗既安全又能获得较好的临床疗效。

参考文献/References:

[1] 郭林杰, 唐承薇. 中国胃肠胰神经内分泌肿瘤临床研究现状分析[J]. 胃肠病学, 2012, 17: 276- 278.
[2] 楼文晖, 吴文铭, 赵玉沛, 等. 胰腺神经内分泌肿瘤治疗指南(2014)[J]. 临床肝胆病杂志, 2014, 52: 1246- 1248.
[3] Frilling A, Modlin IM, Kidd M, et al. Recommendations for management of patients with neuroendocrine liver metastases[J]. Lancet Oncol, 2014, 15: e8- e21.
[4] Minami CA, Bilimoria KY. Databases as vehicles for comparative effectiveness research[J]. J Natl Compr Canc Netw, 2015, 13: 1585- 1588.
[5] Yuan CH, Wang J, Xiu DR, et al. Meta- analysis of liver resection versus nonsurgical treatments for pancreatic neuroendocrine tumors with liver metastases[J]. Ann Surg Oncol, 2016, 23: 244- 249.
[6] Anthony LB. Practical guide to supportive care of patients with functional neuroendocrine tumors[J]. Semin Oncol, 2013, 40: 45- 55.
[7] Kvols LK, Turaga KK, Strosberg J, et al. Role of interventional radiology in the treatment of patients with neuroendocrine metastases in the liver[J]. J Natl Compr Canc Netw, 2009, 7: 765- 772.
[8] Zhang S, Li YX, Li NS, et al. Octreotide acetate long- acting release in treatment of pancreatic neuroendocrine tumors[J]. Chin Med J(Engl), 2009, 122: 1582- 1584.
[9] Knigge U, Hansen CP, Stadil F. Interventional treatment of neuroendocrine liver metastases[J]. Surgeon, 2008, 6: 232- 239.
[10] Pavel M, Baudin E, Couvelard A, et al. ENETS consensus guidelines for the management of patients with liver and other distant metastases from neuroendocrine neoplasms of foregut, midgut, hindgut, and unknown primary[J]. Neuroendocrinology, 2012, 95: 157- 176.
[11] 吴勇超, 李智岗. 肝脏转移瘤血供的影像及病理研究[J]. 介入放射学杂志, 2012, 21: 520- 523.
[12] 陈锦秀, 任 静, 王 闽, 等. MRI动态增强扫描在肝转移瘤诊断及血供分析中的应用(附60例病例报告)[J]. 肿瘤预防与治疗, 2010, 23: 53- 55.
[13] 隋燕霞, 党诚学, 张 勇, 等. 原发性胰腺神经内分泌肿瘤60例临床病理分析[J]. 临床与实验病理学杂志, 2015, 31: 873- 876.
[14] Pathak S, Dash I, Taylor MR, et al. The surgical management of neuroendocrine tumour hepatic metastases[J]. Eur J Surg Oncol, 2013, 39: 224- 228.
[15] Kennedy A, Bester L, Salem R, et al. Role of hepatic intra- arterial therapies in metastatic neuroendocrine tumours (NET): guidelines from the NET- Liver- Metastases Consensus Conference[J]. HPB(Oxford), 2015, 17: 29- 37.
[16] Hur S, Chung JW, Kim HC, et al. Survival outcomes and prognostic factors of transcatheter arterial chemoembolization for hepatic neuroendocrine metastases[J]. J Vasc Interv Radiol, 2013, 24: 947- 956.
[17] 李晓光, 金征宇, 潘 杰, 等. 肝动脉化疗或栓塞治疗胰腺神经内分泌肿瘤肝转移的疗效分析[J]. 介入放射学杂志, 2010, 19: 442- 446.
[18] 房星宇, 于 淼, 杨倚天, 等. 肝动脉化疗栓塞及射频消融治疗胰腺神经内分泌肿瘤肝转移的疗效和生存分析[J]. 介入放射学杂志, 2013, 22: 377- 380.

相似文献/References:

[1]刘秋松,张恭良,李彦豪,等.肝脏神经内分泌肿瘤血管造影表现与生存分析 [J].介入放射学杂志,2017,(04):318.
 LIU Qiusong,ZHANG Gongliang,LI Yanhao,et al.Hepatic neuroendocrine tumors: its angiographic manifestations and the analysis of patient survival[J].journal interventional radiology,2017,(05):318.

备注/Memo

备注/Memo:
(收稿日期:2018-08-31)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2019-05-11