[1]林志鹏,陈斯良,赵剑波.乙型肝炎肝硬化患者肝静脉压力梯度与门静脉压力梯度相关性及临床价值[J].介入放射学杂志,2019,28(02):120-123.
 LIN Zhipeng,CHEN Siliang,ZHAO Jianbo..The correlation between hepatic venous pressure gradient and portal pressure gradient and its clinical value in patients with hepatitis B cirrhosis[J].journal interventional radiology,2019,28(02):120-123.
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乙型肝炎肝硬化患者肝静脉压力梯度与门静脉压力梯度相关性及临床价值()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
28
期数:
2019年02期
页码:
120-123
栏目:
血管介入
出版日期:
2019-02-25

文章信息/Info

Title:
The correlation between hepatic venous pressure gradient and portal pressure gradient and its clinical value in patients with hepatitis B cirrhosis
作者:
林志鹏 陈斯良 赵剑波
Author(s):
LIN Zhipeng CHEN Siliang ZHAO Jianbo.
Department of Interventional Radiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province 510515, China
关键词:
【关键词】 肝硬化 门静脉高压症 经颈静脉肝内门体分流术 肝静脉压力梯度 门静脉压力梯度
文献标志码:
A
摘要:
【摘要】 目的 探讨乙型肝炎肝硬化患者门静脉压力梯度(PPG)与肝静脉压力梯度(HVPG)间相关性及其临床价值。方法 收集2016年6月至2017年12月在南方医科大学南方医院接受经颈静脉肝内门体分流术(TIPS)乙型肝炎肝硬化患者肝静脉楔入压(WHVP)、肝静脉游离压(FHVP)、下腔静脉压(IVCP)、门静脉压(PVP)资料,同时计算HVPG和PPG,Spearman秩和检验分析WHVP与PVP、FHVP与IVCP、HVPG与PPG相关性。结果 17例患者符合入组条件,平均WHVP、PVP分别为(25.88±6.40) mmHg、(27.65±6.20) mmHg,两者呈正相关(r=0.914,P<0.01),斜率为0.883;平均FHVP、IVCP分别为(7.24±2.80) mmHg、(7.76±2.90) mmHg,两者呈正相关(r=0.815,P<0.01),斜率为0.847;平均HVPG、PPG分别为(18.65±6.60) mmHg、(19.94±6.56) mmHg,两者呈正相关(r=0.875,P<0.01),斜率为0.868。结论 乙肝后肝硬化患者HVPG与PPG、WHVP与PVP、FHVP与IVCP有较好相关性,临床上可用HVPG反映乙肝后肝硬化患者PPG。

参考文献/References:

[1] Kim TY, Lee JG, Sohn JH, et al. Hepatic venous pressure gradient predicts Long- term mortality in patients with decom- pensated cirrhosis[J]. Yonsei Med J, 2016, 57: 138- 145.
[2] 陈 辉, 吕 勇, 王秋和, 等. 经颈静脉肝内门体分流术专家共识[J]. 临床肝胆病杂志, 2017, 33: 1218- 1228.
[3] 汤善宏, 秦建平, 束庆飞, 等. TIPS 术中引导门静脉分支穿刺方法[J]. 介入放射学杂志, 2014, 23: 640- 643.
[4] Thalheimer U, Leandro G, Samonakis DN, et al. Assessment of the agreement between wedge hepatic vein pressure and portal vein pressure in cirrhotic patients[J]. Dig Liver Dis, 2005, 37: 601- 608.
[5] Suk KT, Kim HC, Namkung S, et al. Diagnostic accuracy of hepatic venous pressure gradient measurement in the prediction of stageⅠcompensated liver cirrhosis in patients with chronic hepatitis B[J]. Eur J Gastroenterol Hepatol, 2013, 25: 1170- 1176.
[6] Addley J, Tham TC, Cash WJ. Use of portal pressure studies in the management of variceal haemorrhage[J]. World J Gastrointest Endosc, 2012, 4: 281- 289.
[7] Garcia- Tsao G, Sanyal AJ, Grace ND, et al. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis[J]. Am J Gastroenterol, 2007, 102: 2086- 2102.
[8] La Mura V, Abraldes JG, Raffa S, et al. Prognostic value of acute hemodynamic response to i.v. propranolol in patients with cirrhosis and portal hypertension[J]. J Hepatol, 2009, 51: 279- 287.
[9] La Mura V, Abraldes JG, Berzigotti A, et al. Right atrial pressure is not adequate to calculate portal pressure gradient in cirrhosis: a clinical- hemodynamic correlation study[J]. Hepatology, 2010, 51: 2108- 2116.
[10] Reverter E, Blasi A, Abraldes JG, et al. Impact of deep sedation on the accuracy of hepatic and portal venous pressure measurements in patients with cirrhosis[J]. Liver Int, 2014, 34: 16- 25.

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备注/Memo

备注/Memo:
(收稿日期:2018-05-08)
(本文编辑:边 佶)
更新日期/Last Update: 2019-02-20