[1]汤学超,王飞宇,张志钢,等.LACBES左心耳封堵器及动物实验可行性研究[J].介入放射学杂志,2017,(01):44-48.
 TANG Xue- chao,WANG Fei- yu,ZHANG Zhi- gang,et al.Feasibility study of the use of left atrial appendage occluder LACBES with animal experiment[J].journal interventional radiology,2017,(01):44-48.
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LACBES左心耳封堵器及动物实验可行性研究 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2017年01期
页码:
44-48
栏目:
实验研究
出版日期:
2017-01-25

文章信息/Info

Title:
Feasibility study of the use of left atrial appendage occluder LACBES with animal experiment
作者:
汤学超 王飞宇 张志钢 阚 通 白 元 游晓华 黄新苗 许旭东龚善石 季佳东 秦永文
Author(s):
TANG Xue- chao WANG Fei- yu ZHANG Zhi- gang KAN Tong BAI Yuan YOU Xiao- hua HUANG Xin- miao XU Xu- dong GONG Shan- shi JI Jia- dong QIN Yong- wen
Department of Cardiology, Affiliated Changhai Hospital, Second Military Medical University, Shanghai 200433, China
关键词:
【关键词】 左心耳封堵器 LACBES封堵器 左心耳封堵术 动物实验
文献标志码:
A
摘要:
【摘要】 目的 介绍一种自主研究开发的LACBES左心耳封堵器,探讨其封堵左心耳的可行性。 方法 选取8只健康杂种犬,经股静脉途径应用LACBES封堵器封堵左心耳,术后测量封堵器压缩比例,造影定性评估残余分流;术前术后监测左心房压,分析左心耳封堵后对左心房压的即时影响。结果8只实验犬均成功植入LACBES左心耳封堵器,封堵器压缩比例为10%~15%。1只封堵术后有少量残余分流。2只术后死亡与操作相关,原因分别为封堵器移位及股动脉穿刺部位血肿,无器械相关死亡发生。术后即刻左心房收缩压升高,由术前(25.4±2.8) mmHg升至(27.5±3.4) mmHg(P<0.05),15 min后恢复至(25.3±2.8) mmHg。结论 LACBES封堵器封堵左心耳即刻成功率高,残余分流率低,左心房收缩压短暂升高,器械相关并发症低,有望应用于临床。

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备注/Memo

备注/Memo:
(收稿日期:2016-10-17)
(本文编辑:边 佶)
更新日期/Last Update: 2017-01-17