[1]唐世伟,赵新建,王忠敏,等.TIPS对比EBL治疗肝硬化食管静脉曲张出血Meta分析[J].介入放射学杂志,2016,(09):761-765.
　TANG Shi- wei,ZHAO Xin- jian,WANG Zhong- min,et al.The treatment of cirrhosis esophageal variceal bleeding： a meta- analysis of TIPS versus EBL[J].journal interventional radiology,2016,(09):761-765.
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TIPS对比EBL治疗肝硬化食管静脉曲张出血Meta分析 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2016年09期
页码:
761-765
栏目:
血管介入
出版日期:
2016-09-25

文章信息/Info

Title:
The treatment of cirrhosis esophageal variceal bleeding： a meta- analysis of TIPS versus EBL
作者:
唐世伟;  赵新建;  王忠敏;  侯蔚蔚;  陈 俊;  王 晨;  吴志龙
Author(s):
TANG Shi- wei;  ZHAO Xin- jian;  WANG Zhong- min;  HOU Wei- wei;  CHEN Jun;  WANG Chen;  WU Zhi- long
Department of Radiology， First Affiliated Hospital， Medical College of Shihezi University， Shihezi， Xinjiang Uygur Autonomous Region 832008， China
关键词:
【关键词】 经颈静脉肝内门体分流术;  内镜下套扎术;  系统评价;  Meta分析
文献标志码:
A
摘要:
【摘要】 目的 系统评价经颈静脉肝内门体分流术（TIPS）对比内镜下套扎术（EBL）治疗肝硬化食管静脉曲张出血。方法 检索PubMed、EMbase、Cochrane、中国知网和中国万方等数据库中TIPS对比EBL治疗肝硬化食管静脉曲张出血的随机对照试验研究文献，检索时限均自建库至2015 年11 月，并追溯各文献中参考文献。2名研究员按照纳入与排除标准独立筛选文献、提取资料并评价质量，采用RevMan 5.3软件作统计学分析。结果 最终6篇文献纳入研究，总病例数413例。Mata分析结果显示，TIPS术后肝性脑病发生率与EBL相比，差异无统计学意义（OR=1.16，95%CI 0.71、1.88，P=0.55）；TIPS术后再出血发生率低于EBL，差异有统计学意义（OR=0.23，95%CI 0.11、0.50，P=0.0002）；两者间总死亡率差异无统计学意义（OR=0.76，95%CI 0.50、1.17，P=0.21），但亚组2 TIPS总死亡率（23%）低于EBL组（43%）。结论 TIPS术后肝性脑病发生率高达24%，与EBL相比差异虽无统计学意义，但应予以重视。TIPS与EBL相比可更好地控制食管静脉曲张出血。非早期TIPS治疗肝硬化食管静脉曲张出血与EBL相比总死亡率相同，但早期TIPS治疗可降低总死亡率。 

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备注/Memo

备注/Memo:
（收稿日期：２０１5-11-29）
（本文编辑：边 佶）
更新日期/Last Update: 2016-09-19