[1]何川东,周 莹,黄 丹,等.宝石CT能谱成像在肝癌经皮肝动脉化疗栓塞术后疗效评估及随访中的应用价值[J].介入放射学杂志,2016,(01):34-39.
 HE Chuan- dong,ZHOU Ying,HUANG Dan,et al.Clinical application of CT gemstone spectral imaging in assessing therapeutic efficacy of transcatheter arterial chemoembolization for hepatocellular carcinoma[J].journal interventional radiology,2016,(01):34-39.
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宝石CT能谱成像在肝癌经皮肝动脉化疗栓塞术后疗效评估及随访中的应用价值 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2016年01期
页码:
34-39
栏目:
肿瘤介入
出版日期:
2016-01-25

文章信息/Info

Title:
Clinical application of CT gemstone spectral imaging in assessing therapeutic efficacy of transcatheter arterial chemoembolization for hepatocellular carcinoma
作者:
何川东 周 莹 黄 丹 王 忠 林 华 王 东 王晋秋 廖丽萍 刘启榆
Author(s):
HE Chuan- dong ZHOU Ying HUANG Dan WANG Zhong LIN Hua WANG Dong WANG Jin- qiu LIAO Li- ping LIU Qi- yu
Department of Radiology, Mianyang Municipal Central Hospital, Mianyang, Sichuan Province 621000, China
关键词:
【关键词】 宝石能谱CT 原发性肝癌 TACE DSA 疗效评估
文献标志码:
A
摘要:
【摘要】 目的 评价宝石CT能谱成像(GSI)对肝癌 TACE术后疗效评估及随访中的应用价值。
方法 选取2013年2月至2014年10月经病理证实为肝癌经TACE术后患者30例进行回顾性分析。所有30例患者TACE术后1~3个月分别行宝石CT能谱扫描及DSA复查,两者平均间隔时间2~4 d。一次CT扫描得出混合能量(QC图)及能谱(Mono)图像,图像后处理采用ADW4.6工作站和GSI- viewer软件。采用2种方法观察,A法观察QC平扫、动脉期及门静脉期;B法观察最佳单能量、碘/水(iodine/water)基物质图及能谱特征。由2名从事腹部影像工作经验丰富的副主任医师分别对图像在后处理工作站上进行独立评价,结果与DSA对照,计算A、B 2种方法的敏感性、特异性等指标,采用χ2检验比较2种方法的诊断能力。结果 30例TACE术后复查患者共检出154个病灶,DSA明确其中100个病灶有强化,54个病灶无强化。A法灵敏度为72.0%(72/100),特异度为77.8%(42/54);B法灵敏度为97.0%(97/100),特异度为94.4%(51/54),两者灵敏度及特异度差异均有统计学意义(χ2=23.04,χ2=7.11,P<0.05)。A法与DSA一致性中等(κ=0.47,P<0.01),B法与DSA一致性良好(κ=0.91,P<0.01)。结论 与常规CT相比,在不增加辐射剂量的前提下,GSI能明显提高小病灶及多发病灶的检出率;GSI根据能谱分析图的不同特征,反映肿瘤的同源性,客观地提示某一病灶是否为复发或转移灶,有效地鉴别肝脏乏血性肿瘤与其他病变,在肝癌TACE术后疗效评估及随访中更加准确。

参考文献/References:

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备注/Memo

备注/Memo:
(收稿日期:2015-05-05)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2016-01-22