[1]郭欢庆,陈赤丹,闫 鹏,等.超选择性肝动脉栓塞术治疗多囊性肝病初步研究[J].介入放射学杂志,2015,(08):676-679.
 GUO Huan- qing,CHEN Chi- dan,YAN Peng,et al.Transcatheter super- selective hepatic arterial embolization for the treatment of polycystic liver disease: a preliminary study[J].journal interventional radiology,2015,(08):676-679.
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2015年08期
页码:
676-679
栏目:
血管介入
出版日期:
2015-08-25

文章信息/Info

Title:
Transcatheter super- selective hepatic arterial embolization for the treatment of polycystic liver disease: a preliminary study
作者:
郭欢庆 陈赤丹 闫 鹏 李任飞 李 威 杨 坡
Author(s):
GUO Huan- qing CHEN Chi- dan YAN Peng LI Ren- fei LI Wei YANG Po
Department of Vascular Intervention, the Affiliated Fourth Hospital of Harbin Medical University, Harbin, Heilongjiang Province 150001, China
关键词:
【关键词】 多囊性肝病 栓塞治疗性 介入放射学 常染色体显性
文献标志码:
A
摘要:
【摘要】 目的 探讨超选择性肝动脉栓塞术(TAE)治疗多囊性肝病(PLD)的安全性及临床疗效。 方法 2011年10月至2013年10月,采用栓塞微粒球Embosphere?誖对14例有明显临床症状的PLD患者施行超选择性TAE术,其中女性11例,男性3例;年龄42~65岁,平均(48±5)岁。术前和术后每3个月行CT肝扫描,同时复查血常规、肝功能。结果 TAE技术成功率为100%。术后随访12~24个月,12例症状明显缓解,2例无效,有效率为85.7%。术后患者症状开始缓解时间平均为(3.2±1.1)个月。术后18个月时CT随访显示肝脏总体积、囊肿总体积较术前分别缩小(19.3±5.6)%、(20.4±7.8)%,差异有统计学意义(P<0.05)。术后患者转氨酶呈一过性升高,无严重并发症发生。结论 采用栓塞微粒球行超选择性TAE治疗PLD疗效可靠、安全性高,可作为传统治疗手段的补充,值得临床推广应用。

参考文献/References:

[参 考 文 献]
[1] Drenth JP, Chrispijn M, Nagorney DM, et al. Medical and surgical treatment options for polycystic liver disease[J]. Hepatology, 2010, 52: 2223- 2230.
[2] Van Keimpema L, De Koning DB, Van Hoek B, et al. Patients with isolated polycystic liver disease referred to liver centres: clinicalcharacterization of 137 cases[J]. Liver Int, 2011, 31: 92- 98.
[3] Everson GT, Helmke SM, Doctor B. Advances in management of polycystic liver disease[J]. Expert Rev Gastroenterol Hepatol, 2008, 2: 563- 576.
[4] Abu- Wasel B, Walsh C, Keough V, et al. Pathophysiology, epidemiology, classification and treatment options for polycystic liver diseases[J]. World J Gastroenterol, 2013, 19: 5775- 5786.
[5] Bistritz L, Tamboli C, Bigam D, et al. Polycystic liver disease: Experience at a teaching hospital[J]. Am J Gastroenterol, 2005, 100: 2212- 2217.
[6] Qian Q, Li AR, King BF, et al. Clinical profile of autosomal dominant polycystic liver disease[J]. Hepatology, 2003, 37: 164- 171.
[7] 阎洁羽, 段 峰, 王茂强. 选择性肝动脉栓塞治疗多囊肝的相关研究[J]. 介入放射学杂志, 2012, 21: 1054- 1058.
[8] Takei R, Ubara Y, Hoshino J, et al. Percutaneous transcatheter hepatic artery embolization for liver cysts in autosomal dominant polycystic kidney disease[J]. Am J Kidney Dis, 2007, 49: 744- 752.
[9] Ubara Y, Takei R, Hoshino J, et al. Intravascular embolization therapy in a patient with an enlarged polycystic liver[J]. Am J Kidney Dis, 2004, 43: 733- 738.
[10] 靳 松, 崔 凯, 孙自强, 等. 多囊肝临床研究进展[J]. 国际外科学杂志, 2013, 40: 264- 267.
[11] Ubara Y. New therapeutic option for autosomal dominant poly- cystic kidney disease patients with enlarged kidney and liver[J]. Ther Apher Dial, 2006, 10: 333- 341.
[12] Park HC, Kim CW, Ro H, et al. Transcatheter arterial embolization therapy for a massive polycystic liver in autosomal dominant polycystic kidney disease patients[J]. J Korean Med Sci, 2009, 24: 57- 61.
[13] Wang MQ, Duan F, Liu FY, et al. Treatment of symptomatic polycystic liver disease: transcatheter super- selective hepatic arterial embolization using a mixture of NBCA and iodized oil[J]. Abdom Imaging, 2013, 38: 465- 473.
[14] 阎洁羽, 段 峰, 王茂强, 等. 超选择性肝动脉栓塞术治疗多囊肝的初步临床研究[J]. 中华放射学杂志, 2012, 46: 1014- 1018.
[15] Yamamoto A, Imai S, Kobatake M, et al. Evaluation of tris- acryl gelatin microsphere embolization with monochromatic X rays: comparison with polyvinyl alcohol particles[J]. J Vasc Interv Radiol, 2006, 17: 1797- 1802.
[16] Bendszus M, Klein R, Burger R, et al. Efficacy of trisacryl gelatin microspheres versus polyvinyl alcohol particles in the preoperative embolization of meningiomas[J]. AJNR Am J Neuroradiol, 2000, 21: 255- 261.
[17] Yu SC, Lok I, Ho SS, et al. Comparison of clinical outcomes of tris- acryl microspheres versus polyvinyl alcohol microspheres for uterine artery embolization for leiomyomas: results of a randomized trial[J]. J Vasc Interv Radiol, 2011, 22: 1229-1235.
[18] 栾韶亮, 郭 伟, 陈 毅, 等. 肝动脉栓塞治疗症状性多囊肝临床疗效初步分析[J]. 山西医科大学学报, 2014, 45: 404- 406.

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备注/Memo

备注/Memo:
(收稿日期:2015-01-10)
(本文编辑:边 佶)
更新日期/Last Update: 2015-08-23