[1]张宏涛,于慧敏,隋爱霞,等.不同直径 125I粒子食管支架的剂量学对比[J].介入放射学杂志,2015,(09):797-800.
 ZHANG Hong- tao,YU Hui- min,SUI Ai- xia,et al.Dosimetry comparison of esophageal stents carrying different diameters of radioactive 125I seeds[J].journal interventional radiology,2015,(09):797-800.
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不同直径 125I粒子食管支架的剂量学对比()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2015年09期
页码:
797-800
栏目:
实验研究
出版日期:
2015-09-25

文章信息/Info

Title:
Dosimetry comparison of esophageal stents carrying different diameters of radioactive 125I seeds
作者:
张宏涛 于慧敏 隋爱霞 吴 娟 高 贞 王 娟
Author(s):
ZHANG Hong- tao YU Hui- min SUI Ai- xia WU Juan GAO Zhen WANG Juan
Department of Oncology, Hebei Provincial People’s Hospital, Shijiazhuang, Hebei Province 050051, China
关键词:
 【关键词】 放射性食管支架 不同直径 肿瘤靶区 剂量
文献标志码:
A
摘要:
【摘要】 目的 研究不同直径125I粒子放射性食管支架在肿瘤靶区的剂量学分布。方法 用激光扫描仪分别扫描画有直径12、14和16 mm的圆形并标记有5 cm刻度的白纸,以JPEG格式存储在计算机桌面上,根据圆形直径模拟相应食管支架并依次分为A、B、C 3组,利用图像转换程序,每组分别创建17层图片,每层图片层距为5 mm,将图片传输到计算机治疗计划系统(TPS)中,模拟不同直径,长度8 cm食管支架,利用TPS勾画肿瘤靶区(gross tumour volume,GTV),以模拟食管支架边界为肿瘤靶区内界,外扩0.5 cm为外界,于第5层面开始勾画环形并且长度为4 cm的靶区,设定相同处方剂量,并于该层面至第13层面于模拟食管支架上先后7次载入0.3、0.4、0.5、0.6、0.7、0.8和0.9 mCi 125I粒子,粒子层间距1 cm,每层平均布源4颗,得出剂量体积直方图(dose volume histogram DVH),记录每组D90、V90。结果 A、B、C 3组的D90分别为(77.24±19.92)、(69.56±25.27)和(56.38±20.08)Gy(F=0.84,P=0.44),差异无统计学意义;A、B、C 3组的V90分别为(77.76±30.73)%、(76.79±25.92)%和(64.10±32.49)%,(F=0.46,P=0.64),差异无统计学意义。结论 放射性食管支架直径为12 mm时,推荐粒子活度为0.6 mCi;直径为14、16 mm时,推荐粒子活度为0.7 mCi,但当直径16 mm,推荐每层布源5颗,该3种直径的食管支架对剂量学参数无明显影响。

参考文献/References:

[参 考 文 献]
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备注/Memo

备注/Memo:
(收稿日期:2014-11-27)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2015-09-23