[1]江 旭,颜红菊,陈文会,等.B型超声引导125I粒子植入治疗溶骨性骨转移瘤18例[J].介入放射学杂志,2015,(04):346-349.
 JIANG Xu,YAN Hong ju,CHEN Wen hui,et al.Ultrasound guided percutaneous 125I seed implantation for the treatment of osteolytic metastases: clinical analysis of 18 cases[J].journal interventional radiology,2015,(04):346-349.
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B型超声引导125I粒子植入治疗溶骨性骨转移瘤18例 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2015年04期
页码:
346-349
栏目:
临床研究
出版日期:
2015-04-25

文章信息/Info

Title:
Ultrasound guided percutaneous 125I seed implantation for the treatment of osteolytic metastases: clinical analysis of 18 cases
作者:
江 旭 颜红菊 陈文会 李 慧 刘敬禹 王卫星 杨聚鹏 杨继金
Author(s):
JIANG Xu YAN Hong ju CHEN Wen hui LI Hui LIU Jing yu WANG Wei xing YANG Ju peng YANG Ji jin.
Department of Interventional Radiology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
关键词:
【关键词】 超声 骨转移 125I粒子 近距离放射治疗
文献标志码:
A
摘要:
【摘要】 目的 观察B型超声(B超)引导下经皮穿刺125I粒子植入姑息性治疗溶骨性骨转移瘤的疗效。方法 对2011年2月至2013年12月收治的18例晚期肿瘤患者的溶骨性骨转移瘤采用B超实时引导经皮穿刺植入125I粒子,术前、术后3 d以及术后1个月根据视觉模拟评分法(VAS)对疼痛评分。所有治疗病灶术后1个月复查CT检测肿瘤大小变化,观察粒子分布情况,必要时重复治疗。根据CT结果,按实体瘤的疗效评价标准(RECIST)评价疗效。结果 18例患者进行33次手术,术后3 d局部疼痛较术前已有明显改善,与术前VAS比较P=0.000,差异有统计学意义。术后1个月疼痛仍能较好控制,P=0.000,差异有显著统计学意义。末次手术后1个月与基线相比观察疗效:CR 0例(0%),PR 11例(61.1%),SD 6例(33.3%),PD 1例(5.6%),局部控制率(CR+PR)61.1%。无严重的放疗并发症。结论 B超引导简便,可重复性好,能安全、有效地引导经皮穿刺125I粒子植入近距离放射治疗溶骨性骨转移瘤,在不采用治疗计划系统(TPS)的情况下,也能获得较好的局部控制率,疼痛缓解显著。

参考文献/References:

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备注/Memo

备注/Memo:
(收稿日期:2014-06-03)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2015-04-28