[1]李家开,张金山. 肺恶性肿瘤射频消融进展及规范化探讨[J].介入放射学杂志,2014,(02):175-180.
 LI Jia? kai,ZHANG Jin? shan.. The research progress and standardization of radiofrequency ablation for lung malignant tumors[J].journal interventional radiology,2014,(02):175-180.
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 肺恶性肿瘤射频消融进展及规范化探讨 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年02期
页码:
175-180
栏目:
综 述
出版日期:
2014-02-28

文章信息/Info

Title:
 The research progress and standardization of radiofrequency ablation for lung malignant tumors
作者:
 李家开 张金山
Author(s):
 LI Jia?蛳 kai ZHANG Jin?蛳 shan.
 Department of Radiology, General Hospital of PLA, Beijing 100853, China
关键词:
 【关键词】 肺肿瘤 射频消融 规范化
文献标志码:
A
摘要:
 【摘要】 射频消融(RFA)是利用热能导致肿瘤组织凝固坏死。经皮途径RFA治疗肝脏恶性肿瘤的成功,促进了射频消融在肺等其他软组织肿瘤的应用。近年来,许多研究证实了RFA是原发性肺癌和有限的肺转移瘤的安全有价值的治疗技术,临床应用也逐渐增多。理论上,RFA更适合于肺肿瘤的治疗,因为肿瘤周围正常肺实质内的气体能起到一种所谓的绝缘效应,提高能量在肿瘤内的沉积。然而,和其他器官相比,肺消融存在很多不同。本文对肺肿瘤RFA的一些关键问题,包括适应证、围手术期准备、技术要求、并发症防治、影像学随访、以及疗效评价等进行讨论。目前,不能手术治疗的早期肺癌和有限的周围肺组织的转移瘤是RFA的最佳适应证。肺组织的特异性要求使用不同的能量。电极针的准确释放和消融过程的细心操作是提高疗效和避免非靶点重要结构损伤的关键。PET/CT是最准确的术后影像学随访方法,但是术后早期判断肿瘤局部进展仍需进一步验证。对于Ⅰ期非小细胞肺癌和有限的肺转移瘤,RFA术后生存率比较满意。

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备注/Memo:
 (收稿日期:2013-07-18)
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