[1]赵晓阳,曹会存,李天晓,等. 经皮肝穿胆道引流术联合125I粒子植入治疗晚期胰腺癌合并梗阻性黄疸[J].介入放射学杂志,2013,(08):650-654.
 ZHAO Xiao? yang,CAO Hui? cun,LI Tian? xiao,et al. PTCD combined with 125I seed implantation for the treatment of advanced pancreatic cancer associated with obstructive jaundice[J].journal interventional radiology,2013,(08):650-654.
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 经皮肝穿胆道引流术联合125I粒子植入治疗晚期胰腺癌合并梗阻性黄疸 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2013年08期
页码:
650-654
栏目:
非血管介入
出版日期:
2013-08-30

文章信息/Info

Title:
 PTCD combined with 125I seed implantation for the treatment of advanced pancreatic cancer associated with obstructive jaundice
作者:
 赵晓阳 曹会存 李天晓 王振豫 曹广劭 刘 健 王玉丹 刘建文
Author(s):
 ZHAO Xiao?蛳 yang CAO Hui?蛳 cun LI Tian?蛳 xiao WANG Zhen?蛳 yu CAO Guang?蛳 shao LIU Jian WANG Yu?蛳 dan LIU Jian?蛳 wen.
  Interventional Therapy Center, Henan Provincial People’s Hospital, Zhengzhou University, Zhengzhou, Henan Province 450003, China
关键词:
 【关键词】 胰腺癌 梗阻性黄疸 PTCD 125I粒子
文献标志码:
A
摘要:
 【摘要】 目的 评价经皮肝穿胆道引流术(PTCD)联合125I粒子植入治疗晚期胰腺癌合并梗阻性黄疸的近期疗效和安全性。方法 23例晚期胰腺癌合并梗阻性黄疸患者,均经临床、CT、MRI检查和病理活检后明确诊断。所有患者先在DSA下行PTCD,1周后在CT下行胰腺癌病灶放射性125I粒子植入。统计患者临床症状改善情况,肿瘤大小变化,术后并发症等。结果 1个月后23例患者黄疸均现减退,血清胆红素较术前明显下降(P < 0.01);临床表现明显疼痛的19例患者中8例患者疼痛完全缓解,8例患者部分缓解,3例无效,疼痛缓解有效率为84.2%。2个月后CT复查,实体肿瘤2例完全缓解,12例部分缓解,4例无变化,5例疾病进展。随访过程中未出现与手术相关重症胰腺炎、胰漏、肠道出血等严重并发症。结论PTCD联合125I粒子植入治疗晚期胰腺癌合并梗阻性黄疸患者安全、有效,能够短时间内改善黄疸症状,控制肿瘤生长,并且具有较好的姑息性止痛效果,明显改善患者生活质量,是一种有效、值得推广的方法。

参考文献/References:

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备注/Memo

备注/Memo:
(收稿日期:2013-03-29) 
更新日期/Last Update: