[1]赵剑波,陈 勇,何晓峰,等.聚四氟乙烯覆膜支架经颈静脉肝内门腔 分流术后分流道再狭窄及影响因素分析[J].介入放射学杂志,2013,(08):629-633.
 ZHAO Jian? bo,CHEN Yong,HE Xiao? feng,et al. Restenosis of the transjugular intrahepatic portosystemic shunt using stent covered with polytetrafluoroethylene and the analysis of its affecting factors[J].journal interventional radiology,2013,(08):629-633.
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聚四氟乙烯覆膜支架经颈静脉肝内门腔 分流术后分流道再狭窄及影响因素分析 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2013年08期
页码:
629-633
栏目:
血管介入
出版日期:
2013-08-30

文章信息/Info

Title:
 Restenosis of the transjugular intrahepatic portosystemic shunt using stent covered with polytetrafluoroethylene and the analysis of its affecting factors
作者:
 赵剑波 陈 勇 何晓峰 曾庆乐 梅雀林 李彦豪
Author(s):
 ZHAO Jian?蛳 bo CHEN Yong HE Xiao?蛳 feng ZENG Qing?蛳 le MEI Que?蛳 lin LI Yan?蛳 hao.
 Department of Interventional Radiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
关键词:
 【关键词】 门脉高压症 经颈静脉肝内门腔分流术 覆膜支架 再狭窄
文献标志码:
A
摘要:
 【摘要】 目的 探讨采用聚四氟四烯(PTFE)覆膜支架行经颈静脉肝内门腔分流术(TIPS)后分流道再狭窄及相关影响因素。方法 2005年10月至2011年7月收治102例门脉高压症患者,均采用PTFE覆膜支架行TIPS手术,其中男82例,女20例,年龄16 ~ 73岁, 平均(52.6 ± 12.6)岁。术前症状为食管胃底静脉曲张大出血(83例)或顽固性腹水(19例),术前肝功能Child?蛳 Pugh评分为5 ~ 10分,平均(6.65 ± 1.66)分。术后随访0 ~ 58个月,平均(19.9 ± 13.3)个月,采用寿命表法得出术后6、12、24、36、48个月的累积分流道开通率,对影响因素采用Cox回归进行单因素和多因素分析。结果 全部102例均在局麻下成功建立肝内门腔覆膜支架分流道,技术成功率100%。门静脉-右房压力梯度由术前(27.57 ± 4.19)mmHg下降为(15.82 ± 2.18)mmHg,差异有统计学意义(t = 22.8,P < 0.01)。术前Child?蛳 Pugh评分为(6.65 ± 1.66)分,术后3个月为(6.46 ± 1.55)分,差异无统计学意义(t = 0.829,P = 0.408)。随访期间确诊出现覆膜支架分流道再狭窄10例,总体一期再狭窄率为9.8%。术后6、12、24、36、48个月的累积分流道通畅率分别为96%、91%、82%、82%、82%。Cox单因素分析示覆膜支架门脉端长度和支架肝静脉端位置评价有统计学意义;多因素分析示后者为独立影响因素(P = 0.004,OR = 27.758,95%CI:2.85 - 270.72)。结论PTFE覆膜支架可以明显提高TIPS术后分流道通畅率,支架肝静脉端位置良好的患者术后分流道再狭窄发生率低,同时不建议覆膜支架门脉端伸入过长。

参考文献/References:

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备注/Memo

备注/Memo:
 (收稿日期:2012-12-21)
更新日期/Last Update: