[1]梁松年,苏洪英,赵 杨,等.磁共振引导下聚焦超声刀治疗子宫肌瘤一年随访评价[J].介入放射学杂志,2013,(03):206-210.
 year outcome LIANG Song? nian,SU Hong? ying,ZHAO Yang,et al.MRI- guided focused ultrasound surgery of uterine fibroids: evaluation of one?[J].journal interventional radiology,2013,(03):206-210.
点击复制

磁共振引导下聚焦超声刀治疗子宫肌瘤一年随访评价()

PDF下载中关闭

分享到:

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2013年03期
页码:
206-210
栏目:
非血管介入
出版日期:
2013-03-25

文章信息/Info

Title:
MRI- guided focused ultrasound surgery of uterine fibroids: evaluation of one?
作者:
梁松年 苏洪英 赵 杨 孙文阁 吴文颖 卢 涛 牛 蒙 徐 克
Author(s):
蛳 year outcome LIANG Song?蛳 nian SU Hong?蛳 ying ZHAO Yang SUN Wen?蛳 ge WU Wen?蛳 ying LU Tao NIU Meng XU Ke.
Department of Radiology, the First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province 110001, China
关键词:
【关键词】 子宫肌瘤 聚焦超声 磁共振
文献标志码:
A
摘要:
【摘要】 目的 评价MRI引导下聚焦超声刀(MRgFUS)治疗子宫肌瘤的安全性、可行性及1年随访结果。方法 对21例症状性子宫肌瘤患者进行MRgFUS治疗。在治疗后即刻行子宫肌瘤增强MR扫描,测量每例肌瘤的无灌注区域体积,评价治疗安全性及病灶消融情况。术后1年随访进行子宫肌瘤症状-生活质量问卷(UFS?蛳 QOL)调查,分析症状严重度评分(SSS),统计患者症状改善及相关不良事件发生情况,并完成子宫肌瘤MRI复查,对比肌瘤前后体积变化。结果 对全部21例患者的23个子宫肌瘤成功进行了MRgFUS治疗,平均每例耗时3 h 50 min,平均每例肌瘤当天治疗后无灌注体积百分比62.86%(25% ~ 99%),术中无严重并发症发生。17例患者接受了术后1年随访,平均SSS降低68.79%,复查MRI显示肌瘤体积平均缩小49.60%,差异均有统计学意义(P < 0.05)。结论 MRgFUS无创治疗子宫肌瘤具有较高的安全性,近期疗效确切。

参考文献/References:

[1] Mikami K, Murakami T, Okada A, et al. Magnetic resonance imaging?蛳 guided focused ultrasound ablation of uterine fibroids: early clinical experience[J]. Radiat Med, 2008, 26: 198 ?蛳 205.[2] Stewart EA. Uterine fibroids[J]. Lancet, 2001, 357: 293 ?蛳 298.[3] 叶 欣, 费兴波. 超声聚焦刀治疗综述[J]. 国外医学肿瘤分册, 2003: 26.[4] Hindley J, Gedroyc WM, Regan L, et al. MRI guidance of focused ultrasound therapy of uterine fibroids: early results[J]. Am J Roentgenol, 2004, 183: 1713 ?蛳 1719.[5] Spies JB, Coyne K, Guaou Guaou N, et al. The UFS?蛳 QOL, a new disease?蛳 specific symptom and health?蛳 related quality of Life questionnaire for leiomyomata[J]. Obstet Gynecol, 2002, 99: 290 ?蛳 300.[6] 彭晶晶, 谭 艳, 魏 东, 等. 高强度聚焦超声刀治疗子宫肌瘤临床研究[J]. 介入放射学杂志, 2010, 19: 875 ?蛳 877.[7] Pron G, Bennett J, Common A, et al. The Ontario uterine fibroid embolization trial. part 2. uterine fibroid reduction and symptom relief after uterine artery embolization for fibroids[J]. Fertil Steril, 2003, 79: 120 ?蛳 127.[8] Rabinovici J, Inbar Y, Revel A, et al. Clinical improvement and shrinkage of uterine fibroids after thermal ablation by magnetic resonance?蛳 guided focused ultrasound surgery[J]. Ultrasound Obstet Gynecol, 2007, 30: 771 ?蛳 777.[9] Bradley LD. Uterine fibroid embolization: a viable alternative to hysterectomy[J]. Am J Obstet Gynecol, 2009, 201: 127 ?蛳 135.[10] Bradley WG Jr. MR?蛳 guided focused ultrasound: a potentially disruptive technology[J]. J Am Coll Radiol, 2009, 6: 510 ?蛳 513.[11] Hudson SB, Stewart EA. Magnetic resonance?蛳 guided focused ultrasound surgery[J]. Clin Obstet Gynecol, 2008, 51: 159 ?蛳 166.[12] Arleo EK, Khilnani NM, Ng A, et al. Features influencing patient selection for fibroid treatment with magnetic resonance?蛳 guided focused ultrasound[J]. J Vasc Interv Radiol, 2007, 18: 681 ?蛳 685.[13] Stewart EA, Rabinovici J, Tempany CM, et al. Clinical outcomes of focused ultrasound surgery for the treatment of uterine fibroids[J]. Fertil Steril, 2006, 85: 22 ?蛳 29.[14] Fukunishi H, Funaki K, Sawada K, et al. Early results of magnetic resonance?蛳 guided focused ultrasound surgery of adenomyosis: analysis of 20 cases[J]. J Minim Invasive Gynecol, 2008, 15: 571 ?蛳 579.[15] Morita Y, Ito N, Hikida H, et al. Non?蛳 invasive magnetic resonance imaging?蛳 guided focused ultrasound treatment for uterine fibroids ?蛳 early experience[J]. Eur J Obstet Gynecol Reprod Biol, 2008, 139: 199 ?蛳 203.[16] Fennessy FM, Tempany CM. MRI?蛳 guided focused ultrasound surgery of uterine leiomyomas[J]. Acad Radiol, 2005, 12: 1158 ?蛳 1166.[17] John KC Chan. Magnetic resonance?蛳 guided focused ultrasound(MRgFUS)treatment of uterine fibroid[J]. Donald School J Ultrasound Obstet Gynecol, 2010, 4: 157 ?蛳 161.

相似文献/References:

[1]张一平,赵景志,乔新荣,等. 动脉灌注化疗联合高强度聚焦超声治疗胰腺癌的临床研究[J].介入放射学杂志,2011,(12):964.
 ZHANG Yi-ping,ZHAO Jing-zhi,QIAO Xin-rong,et al.Transarterial infusion chemotherapy combined with high intensity focused ultrasound for the treatment of pancreatic carcinomas a clinical study[J].journal interventional radiology,2011,(03):964.
[2]徐 强,黄优华,石红建,等. 葡聚糖微球经子宫动脉栓塞子宫肌瘤的临床疗效[J].介入放射学杂志,2011,(12):961.
 XU Qiang,HUANG You-hua,SHI Hong-jian,et al.The clinical application of uterine arterial embolization with dextran microspheres in treating uterine leiomyomas[J].journal interventional radiology,2011,(03):961.
[3]陈春林,徐玉静,刘 萍,等.子宫肌瘤数字化三维动脉血管网的构建和意义[J].介入放射学杂志,2012,(01):35.
 CHEN Chun-lin,XU Yu-jing,LIU Ping,et al.The construction of digital 3D arterial vascular network of uterine[J].journal interventional radiology,2012,(03):35.
[4]张宇慧,周顺科.子宫肌瘤介入治疗近展[J].介入放射学杂志,2013,(04):340.
 ZHANG Yu? hui,ZHOU Shun? ke..Recent advances in uterine artery embolization for the treatment of symptomatic uterine fibroids[J].journal interventional radiology,2013,(03):340.
[5]赵振华,王 挺,卢增新,等.子宫动脉栓塞治疗单发和多发子宫肌瘤远期疗效对比分析[J].介入放射学杂志,2013,(07):557.
 ZHAO Zhen? hua,WANG Ting,LU Zeng? xin,et al.Uterine artery embolization for uterine leiomyomas: a comparison between solitary and multiple uterine leiomyomas[J].journal interventional radiology,2013,(03):557.

备注/Memo

备注/Memo:
(收稿日期:2012-11-14)
更新日期/Last Update: