[1]徐国斌,易广新,熊斌,等.原发性肝癌术后早期肝内复发转移36例的介入治疗[J].介入放射学杂志,2013,(04):325-328.
 XU Guo? bin,YI Guang? xin,XIONG Bin,et al.Interventional treatment of early intrahepatic recurrence or metastasis of primary liver carcinoma after surgical resection: initial experience of 36 cases[J].journal interventional radiology,2013,(04):325-328.
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原发性肝癌术后早期肝内复发转移36例的介入治疗()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2013年04期
页码:
325-328
栏目:
临床研究
出版日期:
2013-04-17

文章信息/Info

Title:
Interventional treatment of early intrahepatic recurrence or metastasis of primary liver carcinoma after surgical resection: initial experience of 36 cases
作者:
徐国斌 易广新 熊斌 鲁植艳 龙清云 卓德强 胡金香 刘骏
Author(s):
XU Guo?蛳 bin YI Guang?蛳 xin XIONG Bin LU Zhi?蛳 yan LONG Qing?蛳 yun ZHUO De?蛳 qiang HU Jin?蛳 xiang LIU Jun?蛳 fang.
Department of Interventional Radiology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province 430071, China
关键词:
【关键词】 原发性肝癌 复发 肝切除术 肝动脉化疗栓塞术
文献标志码:
A
摘要:
【摘要】 目的 探讨原发性肝癌手术切除术后早期(6个月内)肝内复发转移经肝动脉化疗栓塞(TACE)治疗的近期疗效。方法 36例原发性肝癌外科术后早期诊断肝内复发转移并接受TACE治疗,根据首次DSA表现分为切缘复发或单发病灶组(n = 15)和肝内多发病灶组(n = 21)。治疗方法为先灌注适量化疗药物,然后以表阿霉素碘油乳剂栓塞肿瘤血管。根据复查CT及甲胎蛋白等临床情况决定是否重复治疗,随访12个月内治疗效果。统计学分析采用两组方差分析和t检验、Fisher精确概率法, 以P < 0.05为差异有统计学意义。结果 肝内多发病灶组在术前肿瘤伴子灶、合并门脉2级分支以上瘤栓、巨块无包膜方面高于局部复发/单发病灶组(P < 0.05)。患者均未出现介入治疗相关严重并发症,总体平均介入治疗次数、术后6个月治疗有效率及12个月生存率分别为(3.0 ± 0.7)次、58.3%、66.7%;两组相比较分别为(3.3 ± 0.8)次比(2.9 ± 0.7)次(t = 1.688,P = 0.101);80.0%比42.9%(P = 0.024);86.7%比52.4% (P = 0.03)。结论 原发性肝癌术后早期复发转移TACE具有一定临床疗效,但对于肝内多发病灶患者12个月生存率较差。

参考文献/References:

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备注/Memo

备注/Memo:
(收稿日期:2012-11-11)
更新日期/Last Update: