[1]隋守光,王世礼,孙 鹏,等.瑞替普酶、尿激酶经导管溶栓治疗急性下肢深静脉血栓的疗效观察[J].介入放射学杂志,2013,(01):57-060.
 SUI Shou? guang,WANG Shi? li,SUN Peng,et al. Catheter- directed thrombolytic therapy with use of reteplase and urokinase for the treatment of acute deep venous thrombosis of lower extremity: an observation of clinical results[J].journal interventional radiology,2013,(01):57-060.
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瑞替普酶、尿激酶经导管溶栓治疗急性下肢深静脉血栓的疗效观察 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2013年01期
页码:
57-060
栏目:
临床研究
出版日期:
2013-01-25

文章信息/Info

Title:
 Catheter- directed thrombolytic therapy with use of reteplase and urokinase for the treatment of acute deep venous thrombosis of lower extremity: an observation of clinical results
作者:
 隋守光 王世礼 孙 鹏 肖 颖 施洪峰
Author(s):
 SUI Shou?蛳 guang WANG Shi?蛳 li SUN Peng XIAO Ying SHI Hong?蛳 feng.
 Department of Vascular and Neurosurgical Intervention, Affiliated Shengli Oil?蛳 field Central Hospital, Binzhou Medical College, Dongying, Shandong Province 257034, China
关键词:
 【关键词】 静脉血栓形成 瑞替普酶 尿激酶 导管溶栓
文献标志码:
A
摘要:
 【摘要】 目的 观察瑞替普酶(rPA)与尿激酶(UK)在急性下肢深静脉血栓(ADVT)溶栓治疗中的临床疗效和不良反应。方法 自2008年12月—2012年5月对40例ADVT患者随机分为2组,每组各20例。2组均采用导管溶栓术(CDT),A组给予rPA每日20 Mu,B组给予UK每日50万 ~ 60万u溶栓,同时加用抗凝、抗血小板药物治疗。观察疗效的临床指标、过敏反应及出血并发症等。结果 rPA组溶栓总有效率为100%,UK组总有效率为95%,组间差异无统计学意义(P > 0.05),rPA溶栓起效迅速,较UK具有良好的时效性。两组的过敏反应及出血差异均无统计学意义(P > 0.05)。结论 rPA和UK都是治疗ADVT疗效肯定、安全的溶栓药物,rPA溶栓起效迅速,较UK具有良好的时效性。 

参考文献/References:

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备注/Memo

备注/Memo:
 (收稿日期:2012-08-31)
更新日期/Last Update: