[1]朱海云,程永德,李跃华. 跨膜转运常数评价2型糖尿病患者下肢肌肉微循环状况[J].介入放射学杂志,2012,(07):547-550.
 ZHU Hai- yun,CHENG Yong- de,LI Yue-hua.. Evaluation of microcirculatory status of lower limb muscles by using K- trans in patients with type 2 diabetes[J].journal interventional radiology,2012,(07):547-550.
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 跨膜转运常数评价2型糖尿病患者下肢肌肉微循环状况 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2012年07期
页码:
547-550
栏目:
血管介入
出版日期:
2012-07-30

文章信息/Info

Title:
 Evaluation of microcirculatory status of lower limb muscles by using K- trans in patients with type 2 diabetes
作者:
 朱海云 程永德 李跃华
Author(s):
 ZHU Hai- yun CHENG Yong- de LI Yue-hua.
 Department of Radiology, No.85 Hospital of PLA, Shanghai 200052, China
关键词:
 【关键词】 2型糖尿病 磁共振成像 微循环 糖尿病足
文献标志码:
A
摘要:
 【摘要】 目的 通过动态对比增强磁共振成像(DCE?蛳 MRI)量化正常人和糖尿病患者经皮血管成形术(PTA)治疗前和治疗后的肌肉微循环状况。方法 收集25例2型糖尿病下肢血管闭塞患者,并选择体重指数相匹配的30名健康志愿者作为对照组,通过DCE?蛳 MRI扫描获得比目鱼肌(SOL)和胫前肌(TA)的跨膜转运常数(K?蛳 trans)值,比较两组间的差异,并记录糖尿病患者在股动脉PTA治疗前、后SOL、TA的K?蛳 trans值变化。结果 对照组TA和SOL的K?蛳 trans值均高于糖尿病组,分别为0.018/0.018比0.009/0.006和0.026/0.021比0.012/0.011,组间差异有统计学意义(P < 0.001)。糖尿病患者的K?蛳 trans值在PTA治疗后增加,与治疗前比较差异有统计学意义(P < 0.001)。结论 糖尿病患者的K?蛳 trans值下降,在PTA治疗后有所改善。K?蛳 trans可以量化下肢肌肉微循环变化,并可用于检测正常人SOL和TA的差异。

参考文献/References:

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备注/Memo

备注/Memo:
 (收稿日期:2012-03-02)
更新日期/Last Update: