[1]陆传新,郑 兴.冠状动脉内尿激酶联合替罗非班治疗急性心肌梗死的疗效分析[J].介入放射学杂志,2010,(10):811-813.
 LU Chuan-xin,ZHENG Xing..Evaluation of intracoronary administration of urokinase and tirofiban in treating acute myocardial infarction with massive thrombus[J].journal interventional radiology,2010,(10):811-813.
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冠状动脉内尿激酶联合替罗非班治疗急性心肌梗死的疗效分析()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2010年10期
页码:
811-813
栏目:
临床研究
出版日期:
2010-10-30

文章信息/Info

Title:
Evaluation of intracoronary administration of urokinase and tirofiban in treating acute myocardial infarction with massive thrombus
作者:
陆传新郑 兴
200433 上海  第二军医大学长海医院心血管科
Author(s):
LU Chuan-xin ZHENG Xing.

Department of Cardiovascular Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, ChinaCorresponding author: ZHENG Xing, E-mail: zhengxing57530@163.Com



 

关键词:
冠状动脉疾病 尿激酶 替罗非班
分类号:
R543.31
文献标志码:
摘要:
目的 观察在急性心肌梗死(AMI)患者急诊经皮冠状动脉介入治疗术(PCI)中,冠状动脉(冠脉)内应用尿激酶联合替罗非班治疗富含血栓病变的安全性和疗效。方法 回顾性分析85例行急诊PCI术AMI患者住院和随访资料,7例患者造影发现其梗死相关动脉(IRA)内血栓负荷明显,对这部分患者冠脉内联合应用尿激酶和替罗非班,术后观察患者TIMI血流分级和心肌灌注,住院期间药物不良反应,住院期间以及随访期主要不良心血管事件(MACE)和心脏彩色多普勒超声。结果 用药后患者冠脉内血栓负荷明显减轻甚至消失,前向血流恢复至TIMI 2 ~ 3级,支架植入后未发生“无复流”或“慢血流”现象,住院期间无MACE事件、严重出血事件发生, 3 ~ 9个月随访亦未发生MACE事件,患者心脏彩超提示左室功能良好,取得了较好的临床疗效。结论 对于富含血栓病变的AMI患者,在急诊PCI中冠脉内联合应用尿激酶和替罗非班安全有效。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:20100402
更新日期/Last Update: 2010-10-30