[1]张福先,张昌明,胡路,等.预置导管溶栓辅助血管成形治疗慢性肢体动脉闭塞性疾病[J].介入放射学杂志,2010,(09):718.
　ZHANG Fuxian,ZHANG Changming,HU Lu,et al.Preparatory catheter－directed thrombolysis together with assisted endovascular angioplasty for the treatment of chronic occlusive arterial disorders of lower extremities[J].journal interventional radiology,2010,(09):718.
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预置导管溶栓辅助血管成形治疗慢性肢体动脉闭塞性疾病()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2010年09期
页码:
718
栏目:
血管介入
出版日期:
2010-09-15

文章信息/Info

Title:
Preparatory catheter－directed thrombolysis together with assisted endovascular angioplasty for the treatment of chronic occlusive arterial disorders of lower extremities
作者:
张福先; 张昌明; 胡路; 冯亚平; 梁刚柱; 张欢
１０００３８北京世纪坛医院血管外科
Author(s):
ZHANG Fu－xian; ZHANG Chang－ming; HU Lu; FENG Ya－ping; LIANG Gang－zhu; ZHANG Huan．
Department of Vascular Surgery，Beijing Shijitan Hospital＆No．９Clinical Hospital of Beijing University，Beijin１０００３８，Chnia Corresponding author：ZHANG Fu－xian，E－mail：fuxian＠２６３．Net
关键词:
慢性肢体闭塞性疾病; 预置导管溶栓; 血管成形术
分类号:
R５４３.５
文献标志码:
A
摘要:
目的探讨预置导管溶栓辅助腔内血管成形对慢性肢体闭塞性疾病治疗的疗效和安全性。方法回顾性总结２００８年１月至２００９年１２月在我院行预置导管溶栓辅助腔内血管成形治疗１２例慢性肢体闭塞性疾病。全部病例均有慢性肢体缺血病史，平均１９．３个月（３～４８个月），间歇性跛行距离为５０～２００米，平均１２５米。１２例中静息痛５例（４２％），足趾坏死３例（２５％），重症肢体缺血４例（３３％）。在全部１２例中踝－肱指数（ABI ）为０～０．６５，平均０．３３。全部病例的病变部位首先被置入导管溶栓（尿激酶、rt－PA），２d后行腔内血管成形（球囊扩张或植入支架）。结果全部１２例患者获得良好的临床效果，其中４例应用rt－PA，８例用尿激酶。病变动脉的闭塞长度在溶栓前为６０～１５０mm，平均８０mm，溶栓后为１０～５０mm，平均为３０mm。全部病例溶栓后成功地完成了血管成形，术后ABI 为０．６４～１．０，平均０．８６，较术前平均提高了０．５３。围手术期，无死亡病例和需要进一步外科干预的并发症。全部患者得到随访１年，原病变血管１００％通畅。结论预置导管溶栓辅助腔内血管成形对慢性肢体闭塞性疾病的治疗是有效的和安全的。可以明显提高临床疗效。

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备注/Memo

备注/Memo:
收稿日期：２０１０－０６－１８
更新日期/Last Update: 2010-09-15