[1]李强,曾从俊,王莺.化疗栓塞联合质子放射治疗肝癌合并门脉主干癌栓的临床应用[J].介入放射学杂志,2009,(04):278.
 LI Qiang,ZENG Congjun,WANG Ying.Interventional chemoembolization combined with proton radiotherapy for the treatment of hepatocellular carcinoma accompanied with portal cancerous thrombus[J].journal interventional radiology,2009,(04):278.
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化疗栓塞联合质子放射治疗肝癌合并门脉主干癌栓的临床应用()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2009年04期
页码:
278
栏目:
肿瘤介入
出版日期:
2009-04-15

文章信息/Info

Title:
Interventional chemoembolization combined with proton radiotherapy for the treatment of hepatocellular carcinoma accompanied with portal cancerous thrombus
作者:
李强曾从俊王莺
215021苏州上海交通大学医学院苏州九龙医院影像科
Author(s):
LI QiangZENG Cong-junWANG Ying.
Department of Radiology,Kowloon Hospital,School of Medicine,Shanghai Jiaotong University,Suzhou215021,China
关键词:
肝细胞门静脉癌栓栓塞治疗性质子放射疗法
分类号:
R735.7
文献标志码:
A
摘要:
目的探讨栓塞化疗联合质子放射治疗肝癌合并门脉主干癌栓的临床效果。方法46例肝癌合并门静脉癌栓患者,接受介入栓塞化疗与质子联合治疗,将质子放射治疗分程并与介入治疗交替进行。评价其近期疗效、放射反应、随访生存率。结果有效率91.3%,门脉癌栓消失率45.6%,肝功能恢复良好,AFP水平显著下降;放疗中或放疗后无一例发生明确的急慢性放射性肝损伤或放射性肝病;1、6个月,1、2年生存率分别为100%、89.1%、52.2%、21.4%,中位生存期17.6个月。结论对于合并门脉癌栓形成的晚期肝癌患者,介入联合质子放射治疗是一种新的安全有效方法。

参考文献/References:

[1]程树群,吴孟超,陈汉,等.肝细胞癌伴门静脉癌栓不同治疗方法的疗效比较[J].中华肿瘤杂志,2005,27:183-185.
[2]Okuda K,Ohtsuki J,Obata H,et al.Natural history of hepatocellular carcinoma and prognosis in relation to treatment :study of850patients[J].Cancer,1985,56:918-928.
[3]程树群,吴孟超,陈汉,

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备注/Memo

备注/Memo:
收稿日期:2008-09-23
更新日期/Last Update: 2009-04-15