[1]王桂红,钱厚龙,曹琪,等.椎体成形术和传统法治疗骨质疏松性椎体压缩骨折疗效的对比研究[J].介入放射学杂志,2008,(09):663.
　WANG Guihong,QIAN Houlong,CAO Qi,et al.Percutaneous vertebroplasty and conservative therapy for osteoporotic vertebral compression fractures：a clinical comparative study[J].journal interventional radiology,2008,(09):663.
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椎体成形术和传统法治疗骨质疏松性椎体压缩骨折疗效的对比研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2008年09期
页码:
663
栏目:
临床研究
出版日期:
2008-09-15

文章信息/Info

Title:
Percutaneous vertebroplasty and conservative therapy for osteoporotic vertebral compression fractures：a clinical comparative study
作者:
王桂红; 钱厚龙; 曹琪; 等
５７１０００江苏省姜堰市人民医院放射科（王桂红、钱厚龙、曹琪、徐美军）；骨科（王国喜）；内科（孙爱民）
Author(s):
WANG Gui－hong; QIAN Hou－long; CAO Qi ; WANG Guo－xi; SUN Ai －min; XU Mei－jun
Department of Radiology，Jiangyan Peoples' Hospital，Jiangyan５７１０００，China
关键词:
椎体成形术; 骨质疏松症; 椎体压缩性骨折; 椎体高度
分类号:
：R６８３.２
文献标志码:
B
摘要:
目的研究并比较椎体成形术（PVP）和保守疗法治疗骨质疏松性椎体压缩骨折的临床疗效。方法骨质疏松性椎体新鲜压缩骨折８３例共１０４节，非随机分为２组，组１共４４例５８节用PVP治疗，组２共３９例４６节用保守治疗，比较两组治疗后随访期内疗效及椎体高度变化。结果组１患者４４例PVP后１周疼痛均得到缓解，视觉疼痛评分（VAS）平均分值从术前８．５下降至２．６（平均下降５．９）。组２患者３９例保守治疗后１周VAS分值无变化，在治疗后１周、１和３个月时。组１的VAS分值明显低于组２（P＜０．０１），６个月时两组差异无统计学意义（P＞０．０５）。平均随访８．９个月，组１有新发骨折３例３节，组２有２例２节，两组比较无显著差异无统计学意义（P＞０．０５）。PVP后１周椎体高度恢复平均为前缘２．２mm，中央２．３mm，后缘高度无变化，随访３、６个月椎体前缘、中央高度与PVP后１周时无差异（P＜０．０１）。保守治疗后１周椎体前缘、中央及后缘高度与治疗前比较无显著改变，３个月时椎体高度丢失平均为前缘１．９mm，中央２．１mm，６个月时与３个月无差异。在治疗３个月后，组１椎体高度明显高于组２（P＜０．０１）。结论PVP可迅速缓解疼痛，明显缩短病程，但６个月后两组疗效无显著差异；PVP可使新鲜压缩椎体的前缘和中央高度得到部分恢复，可显著预防椎体进一步塌陷；保守治疗在３个月内椎体高度可进一步丢失；PVP后新发骨折可能是骨质疏松症的自然发病过程。

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备注/Memo

备注/Memo:
收稿日期：２００８－０２－２６
更新日期/Last Update: 2008-09-15