[1]曹野,王进,聂勇,等.经泵动脉灌注抗癌药治疗雄激素非依赖性前列腺癌的疗效评价[J].介入放射学杂志,2008,(09):641.
 CAO Ye,WANG Jin,NIE Yong,et al.Clinical evaluation of internal iliac artery anticancer drug infusion for the treatment of androgen-independent prostate cancer[J].journal interventional radiology,2008,(09):641.
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经泵动脉灌注抗癌药治疗雄激素非依赖性前列腺癌的疗效评价()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2008年09期
页码:
641
栏目:
肿瘤介入
出版日期:
2008-09-15

文章信息/Info

Title:
Clinical evaluation of internal iliac artery anticancer drug infusion for the treatment of androgen-independent prostate cancer
作者:
曹野王进聂勇
443000湖北宜昌市第一人民医院介入放射科(曹野、陈华、黄新阶);泌尿外科(王进、聂勇)
Author(s):
CAO Ye WANG JinNIE YongCHEN HuaHUANG Xin-jie.
Depart-ment of Interventional Radiology,Yichang Municipal First People's Hospital,Yichang443000,China
关键词:
雄激素非依赖性前列腺癌髂内动脉灌注化疗预后
分类号:
R737.25
文献标志码:
A
摘要:
目的观察经髂内动脉灌注化疗治疗雄激素非依赖性前列腺癌(AIPC)的临床疗效。方法38例确诊AIPC患者按治疗时间先后随机分为介入治疗组与对照组,其中介入治疗组23例在内分泌治疗(药物加手术去势)同时行双侧髂内动脉定期灌注化疗,对照组15例采用内分泌治疗,观察并比较两组疗效。结果介入治疗组临床症状明显减轻,最大尿流率在治疗后6个月明显改善,与对照组比较差异有统计学意义(P<0.05),经2年随访,介入治疗组与对照组总有效率分别为65.2%与26.7%,两者相比差异有统计学意义(P<0.05)。结论经双侧髂内动脉灌注化疗治疗AIPC疗效肯定,可显著改善临床症状与生活质量。

参考文献/References:

[1]高江平,洪宝发.雄激素非依赖性前列腺癌的治疗策略[J].中华泌尿外科杂志,2005,26:286.
[2]贺松琴.雄激素非依赖性前列腺癌发生的分子机制[J].国外医学:泌尿外科分册,2005,25:811.
[3]沈华锋,郑祥毅.雄激素受体与激素非依赖性前列腺癌[J].国外医学:泌尿外科分册,2005,25:461.
[4]Buhley GJ ,Carducci M,Dahut W,et al.Eligibility and resp-onse guidelines for phaseⅡclinical trials in androgen-independent prostate cancer:recommendations from the Prostate-Specific Antigen Working Group[J].J Clin Oncol,1999,17:3461-3467.
[5]常钢,陈志强,杨志刚,等.前列腺动脉造影表现及方法探讨[J].介入放射学杂志,2004,13:29-30.

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备注/Memo

备注/Memo:
收稿日期:2008-04-07
更新日期/Last Update: 2008-09-15