[1]焦德超,张福君,陆郦工,等.125Ⅰ粒子组织间植入治疗肺恶性肿瘤[J].介入放射学杂志,2008,(03):190.
 JIAO Dechao,ZHANG Fujun,LU Ligong,et al.CT guided radioactive125Ⅰseed implantation in treating lung malignant tumors[J].journal interventional radiology,2008,(03):190.
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2008年03期
页码:
190
栏目:
非血管介入
出版日期:
2008-03-15

文章信息/Info

Title:
CT guided radioactive 125 Ⅰseed implantation in treating lung malignant tumors
作者:
焦德超张福君陆郦工
510060广州中山大学肿瘤防治中心影像介入科,华南肿瘤学国家重点实验室(焦德超、张福君、吴月霞、李传行,段光峰);广东省人民医院(陆郦工)
Author(s):
JIAO De-chaoZHANG Fu-junLU Li-gongWU Yue-xiaLI Chuan-xingDUAN Guang-feng.
Department of Medical Imaging and Interventional Radiology,Cancer Center,Sun Yat-sen University,South China State Key Laboratory of Oncology.Guangzhou510060,China
关键词:
肺肿瘤放射性核素介入性临床研究
分类号:
R734.2
文献标志码:
A
摘要:
目的评价CT导向下 125 Ⅰ粒子植入治疗肺恶性肿瘤的临床价值。方法32例肺恶性肿瘤患者,其中18例为肺癌,共20个病灶;14例为肺转移瘤(原发病9例为肝癌,4例为肠癌,1例为乳腺癌),共28个病灶。病灶平均直径为5.5cm。采用治疗计划系统(TPS)计算布源,在CT导向下将 125 Ⅰ粒子植入瘤灶内。结果32例共48个病灶,完全缓解(CR)25个;部分缓解(PR)15个;无变化(NC)7个;进展(PD)1个,总有效率83.3%。术中肺内有少量渗出;2例出现气胸,肺压缩均在30%以内,经保守治疗好转;术后1周痰中带血15例;术后2周2例出现轻度白细胞下降,白细胞计数(3~4)×10 9 /L;术后2个月的影像学检查发现肺内粒子游走2例;未见其他严重并发症。结论放射性粒子植入治疗肺恶性肿瘤,近期效果好,是治疗肺恶性肿瘤的简便、安全、有效的方法。

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备注/Memo

备注/Memo:
收稿日期:2008-01-10
更新日期/Last Update: 2008-03-15