[1]任志忠,刘 影,岳元勋,等.明胶海绵微粒- TACE治疗15例大肝癌术后外周血Treg细胞的变化及意义[J].介入放射学杂志,2018,27(12):1151-1154.
　REN Zhizhong,LIU Ying,YUE Yuanxun,et al.Postoperative changes and its significance of Treg cells in peripheral blood after GSMs- TACE treatment for large hepatocellular carcinoma in 15 patients[J].journal interventional radiology,2018,27(12):1151-1154.
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明胶海绵微粒- TACE治疗15例大肝癌术后外周血Treg细胞的变化及意义()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
27
期数:
2018年12期
页码:
1151-1154
栏目:
肿瘤介入
出版日期:
2018-12-25

文章信息/Info

Title:
Postoperative changes and its significance of Treg cells in peripheral blood after GSMs- TACE treatment for large hepatocellular carcinoma in 15 patients
作者:
任志忠;  刘 影;  岳元勋;  杨晓伟;  黄 鑫;  张跃伟
Author(s):
REN Zhizhong;  LIU Ying;  YUE Yuanxun;  YANG Xiaowei;  HUANG Xin;  ZHANG Yuewei.
Department of Hepatobiliary Intervention， Affiliated Beijing Tsinghua Changgung Hospital， School of Clinical Medicine， Tsinghua University， Beijing 102218， China
关键词:
【关键词】 肝细胞肝癌;  肝动脉化疗栓塞术;  调节性T淋巴细胞;  明胶海绵微粒
文献标志码:
A
摘要:
【摘要】 目的 初步探讨应用明胶海绵微粒（GSMs）行TACE治疗大肝癌术后外周血中调节性T淋巴细胞（Treg）变化及意义。方法 应用流式细胞技术检测健康组和大肝癌患者GSMs- TACE术前与术后第10天、第22天外周血Treg细胞的含量。结果 选择健康人7名，符合入组标准的肝癌患者共计15例。外周血中Treg细胞含量：健康对照组为（8.64±1.94）%；肝癌患者术前为（11.52±3.78）%，术后第10天为（9.07±1.94）%，与术前相比显著下降（P=0.039），术后第22天为（9.96±1.48）%，与术前比较差异有统计学意义（P=0.028）。结论 GSMs- TACE治疗大肝癌能够显著降低外周血Treg细胞的含量，表明该方法对机体免疫功能有正向调节作用。

参考文献/References:

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备注/Memo

备注/Memo:
（收稿日期：２０１8-０8-14）
（本文编辑：俞瑞纲）
更新日期/Last Update: 2018-12-20