[1]李建伟,纪盛章,宋金玉,等.颈内动脉狭窄局部的流固耦合有限元分析 [J].介入放射学杂志,2018,27(05):447-450.
 LI Jianwei,JI Shengzhang,SONG Jinyu,et al.Fluid structure interaction finite element analysis of local internal carotid artery stenosis[J].journal interventional radiology,2018,27(05):447-450.
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颈内动脉狭窄局部的流固耦合有限元分析 
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
27
期数:
2018年05期
页码:
447-450
栏目:
实验研究
出版日期:
2018-05-25

文章信息/Info

Title:
Fluid structure interaction finite element analysis of local internal carotid artery stenosis
作者:
李建伟 纪盛章 宋金玉 郑 珺
Author(s):
LI Jianwei JI Shengzhang SONG Jinyu ZHENG Jun
Department of Radiology, Tianjin Municipal No.4 Central Hospital, Tianjin 300140, China
关键词:
【关键词】 流固耦合 颈内动脉狭窄 粥样硬化斑块 血流动力学
文献标志码:
A
摘要:
【摘要】 目的 研究不同狭窄程度颈内动脉的血流动力学特点,探索颈内动脉狭窄局部粥样硬化斑块形成和发展机制。方法 基于颈动脉CTA图像构建颈内动脉轻、中、重度狭窄模型,并予流固耦合(FSI)有限元分析,检测1个心动周期内颈内动脉狭窄近端、喉部和远端的壁面压力(WP)、壁面剪切力(WSS)和血流速度。结果 随着狭窄程度增加,WP在狭窄喉部和狭窄远端明显降低;WSS在狭窄喉部逐渐增大,在狭窄两端逐渐减小;血流速度在狭窄喉部增加,在狭窄两端减低,且狭窄远端湍流越发明显。结论 随着颈内动脉狭窄程度增加,脑供血量逐渐降低,缺血性脑卒中和狭窄处斑块易损概率增大,促进狭窄远端更易形成斑块。基于FSI有限元分析,可对不同颈内动脉狭窄局部粥样硬化发生和发展作出客观评价,有助于临床预防和治疗评估。

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相似文献/References:

[1]刘 莹,章德发,殷艳飞,等.颈动脉双向流固耦合模型非稳态血流数值分析[J].介入放射学杂志,2015,(10):885.
 LIU Ying,ZHANG De- fa,YIN Yan- fei,et al.Numerical analysis of unsteady blood flow model of fluid- solid interaction in carotid artery[J].journal interventional radiology,2015,(05):885.
[2]李建伟,纪盛章,宋金玉.流固耦合分析脉压差对颈内动脉狭窄处壁面剪切力的影响[J].介入放射学杂志,2023,32(11):1131.
 LI Jianwei,JI Shengzhang,SONG Jinyu..Fluid structure interaction analysis of the effect of pulse pressure difference on the wall shear stress at the stenosis of internal carotid artery[J].journal interventional radiology,2023,32(05):1131.

备注/Memo

备注/Memo:
(收稿日期:2017-05-31)
(本文编辑:边 佶)
更新日期/Last Update: 2018-05-13