[1]颜 波,施瑞华,冯亚东,等.新型可降解食管支架动物实验研究[J].介入放射学杂志,2016,(02):155-159.
 YAN Bo,SHI Rui- hua,FENG Ya- dong,et al.A novel biodegradable esophageal stent: an experimental study in pigs[J].journal interventional radiology,2016,(02):155-159.
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新型可降解食管支架动物实验研究 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2016年02期
页码:
155-159
栏目:
实验研究
出版日期:
2016-02-25

文章信息/Info

Title:
A novel biodegradable esophageal stent: an experimental study in pigs
作者:
颜 波 施瑞华 冯亚东 冷德嵘 狄镇海
Author(s):
YAN Bo SHI Rui- hua FENG Ya- dong LENG De- rong DI Zhen- hai
Department of Interventional Radiology, Afflicated Hospital of Jiangsu University, Zhenjiang, Jiangsu Province 212000, China
关键词:
【关键词】 食管肿瘤 可降解支架 动物实验
文献标志码:
A
摘要:
【摘要】 目的 通过动物实验探讨新型可降解食管支架的安全性和降解性能。方法 用模具以医用聚对二氧环己酮(PPDO)编制成新型分段的可降解食管支架。选择实验用巴马猪9头,植入新型可降解食管支架。术后每周1次胃镜检查,直至支架降解滑落。胃镜下观察支架降解情况、周围黏膜增生情况及可能的并发症。结果 术后第3周支架颜色渐由蓝色变成灰白色,支架丝材变细,支架网眼增大明显;第7周支架丝材发生断裂现象;第8周支架完全降解滑落。支架植入后食管组织开始增生,3周时增生达顶点,4~7周时增生渐减轻,8周时食管黏膜恢复正常。结论 新型PPDO可降解食管支架是安全的,均未发生严重并发症,支架所致食管组织增生反应可恢复,有一定的临床应用前景。

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备注/Memo

备注/Memo:
(收稿日期:2015-05-26)
(本文编辑:边 佶)
更新日期/Last Update: 2016-02-22