[1]宋 杰,王黎洲,李 兴,等.中晚期胃癌行介入灌注化疗栓塞术的疗效评估[J].介入放射学杂志,2014,(11):996-1000.
 SONG Jie,WANG Li zhou,LI Xing,et al.Evaluation of therapeutic effect of interventional perfusion chemoembolization in treating advanced gastric cancers[J].journal interventional radiology,2014,(11):996-1000.
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中晚期胃癌行介入灌注化疗栓塞术的疗效评估 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年11期
页码:
996-1000
栏目:
临床研究
出版日期:
2014-11-25

文章信息/Info

Title:
Evaluation of therapeutic effect of interventional perfusion chemoembolization in treating advanced gastric cancers
作者:
宋 杰 王黎洲 李 兴 蒋天鹏 吴晓萍 周 石
Author(s):
SONG Jie WANG Li zhou LI Xing JIANG Tian peng WU Xiao ping ZHOU Shi.
Department of Radiology, Affiliated Hospital of Guiyang Medical College, Guiyang, Guizhou Province 550004, China
关键词:
【关键词】 中晚期胃癌 介入治疗 化疗栓塞 疗效
文献标志码:
A
摘要:
【摘要】 目的 探讨并评估介入灌注化疗栓塞术治疗中晚期胃癌的价值和临床疗效。方法 回顾性分析我科2010年1月—2013年1月接受介入灌注化疗栓塞治疗的中晚期胃癌患者44例,术后随访6个月至2年。对术前及术后临床症状的改善,肿瘤病灶的大小等资料进行分析比较。结果 介入治疗后上腹饱胀、疼痛临床症状缓解的患者有37例(37/44,84.1%),恶心、呕吐临床症状缓解的患者有24例(24/28,85.7%),10例粪便潜血试验阳性者7例转阴,8例存在腹水的患者未缓解;10例介入治疗肿瘤降期后接受外科手术切除治疗。进行6、12和24个月的随访,患者的生存率分别为81.8%(36/44)、59.1%(26/44)、18.2%(8/44)。结论 介入灌注化疗栓塞术治疗是安全、有效的,能改善患者的临床症状并降低其肿瘤分期,治疗中晚期胃癌近期及中期疗效较满意,远期疗效的评估有待进一步随访。

参考文献/References:

[1] Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008[J]. Int J Cancer, 2010, 127: 2893 2917.
[2] Jaffer AA. NCCN clinical practice guidelines in oneology: gastric cancer[M]. Bethesda: National Comprehensive Cancer Network, 2011.
[3] Al Batran SE, Atmaca A, Hegewisch Becker S, et al. Phase Ⅱ trial of biweekly infusional fluorouracil, folinic acid, and oxaliplatin in patients with advanced gastric cancer[J]. J Clin Oncol, 2004, 22: 658 663.
[4] De Vita F, Orditura M, Matano E, et al. A phase II study of biweekly oxaliplatin plus infusional 5 fluorouracil and folinic acid (FOLFOX 4) as first line treatment of advanced gastric cancer patients[J]. Br J Cancer, 2005, 92: 1644 1649.
[5] Liu ZF, Guo QS, Zhang XQ, et al. Biweekly oxaliplatin in combination with continuous infusional 5 fluorouracil and leucovorin (modified FOLFOX 4 regimen) as first line chemotherapy for elderly patients with advanced gastric cancer[J]. Am J Clin Oncol, 2008, 31: 259 263.
[6] P’eng FK, Wul C, Changl TJ, et al. a comparison of regional versus systemic drug injection adriamycin concentration in peripheral blood and gastric stump(post Billroth Ⅱgastrectomy)in the dog[J]. Cancer Chemother Pharmacol, 1989, 23: 363 366.
[7] Shchepotin IB, Chomy V, Hanfelt J, et al. Palliative superselective intra arterial chemotherapy for advanced nonresectable gastric cancer[J]. J Gastrointest Surg, 1999, 3: 426 431.
[8] 高 峰, 黄祥忠, 任冬青, 等. 经动脉灌注化疗联合不同化疗方法治疗进展期胃癌60例对照研究[J]. 介入放射学杂志, 2013, 22: 857 859.
[9] Shiochi H, Yamada M, Kishina M, et al. A case of AFP producing gastric cancer responding to the combination of systemic chemotherapy, transcatheter arterial embolization and hepatic infusion chemotherapy[J]. Gan To Kagaku Ryoho, 2009, 36: 843 846.

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备注/Memo

备注/Memo:
(收稿日期:2014-04-19)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2014-11-24